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Rapid Communication | Open Access

Transcriptomic landscapes underlying response and resistance to HDAC inhibitor chidamide in triple-negative breast cancer

Yanxia Zhanga,b,1, Yunduo Liua,c,1, Mei Zhanga,1, Guanjie Lid, Qin Xianga, Shunhong Wua, Keping Xieb( ), Bin Xiaoe( ), Linhai Lia( )
Department of Laboratory Medicine, The Affiliated Qingyuan Hospital (Qingyuan People’s Hospital), Guangzhou Medical University, Qingyuan, Guangdong 511518, China
School of Medicine, The South China University of Technology, Guangzhou, Guangdong 510006, China
School of Public Health, Dali University, Dali, Yunnan 671003, China
Thyroid and Breast Specialty of General Surgery Area Five, The Affiliated Qingyuan Hospital (Qingyuan People’s Hospital), Guangzhou Medical University, Qingyuan, Guangdong 511518, China
Department of Laboratory Medicine, Southern Medical University Hospital of Integrated Traditional Chinese and Western Medicine, Southern Medical University, Guangzhou, Guangdong 510315, China

1 These authors contributed equally to this work.

Peer review under responsibility of Chongqing Medical University.

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Genes & Diseases
Volume 13 Issue 1,
January 2026
DOI: 10.1016/j.gendis.2025.101676

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Cite this article:
Zhang Y, Liu Y, Zhang M, et al. Transcriptomic landscapes underlying response and resistance to HDAC inhibitor chidamide in triple-negative breast cancer. Genes & Diseases, 2026, 13(1). https://doi.org/10.1016/j.gendis.2025.101676

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Received: 13 June 2024
Published: 08 May 2025
© 2025 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).