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Rapid Communication | Open Access

MyoAAV-delivered sup-tRNA increases full-length dystrophin expression

Xiuyi Aia,1, Yue Changa,1, Ruo Wub,c,1, Jie Liub,c, Pei Zhanga, Yayu Wanga, Zhuoyin Zhenga, Shu Zhanga( ), Yongchang Chenb,c,d( ), Shiwen Wua( )
Department of Neurology, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China
State Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, Yunnan 650500, China
Yunnan Key Laboratory of Primate Biomedical Research, Kunming, Yunnan 650500, China
Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan 650500, China

1 These authors contributed equally.

Peer review under the responsibility of the Genes & Diseases Editorial Office, in alliance with the Association of Chinese Americans in Cancer Research (ACACR, Baltimore, MD, USA)

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Genes & Diseases
Volume 12 Issue 5,
September 2025
Article number: 101666
DOI: 10.1016/j.gendis.2025.101666

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Cite this article:
Ai X, Chang Y, Wu R, et al. MyoAAV-delivered sup-tRNA increases full-length dystrophin expression. Genes & Diseases, 2025, 12(5): 101666. https://doi.org/10.1016/j.gendis.2025.101666

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Received: 30 October 2024
Published: 03 May 2025
© 2025 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).