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Rapid Communication | Open Access

Sirolimus may improve bile excretion in ABCB11 mutants: A case report of a patient with bile salt export pump deficiency

Tao Zenga,1, Jiahui Panga,1, Yutian Chonga, Guofang Tangb, Yingying Liaoa, Xianghao Caia, Xiaolong Xiaoa, Yibo Zhanga, Shuru Chena( ), Xinhua Lia( )
Department of Infectious Diseases, Key Laboratory of Liver Disease of Guangdong Province, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong 510630, China
Institute of Infectious Diseases, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, Guangdong 510440, China

Peer review under the responsibility of the Genes & Diseases Editorial Office, in alliance with the Association of Chinese Americans in Cancer Research (ACACR, Baltimore, MD, USA).

1 These authors contributed equally.

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Genes & Diseases
Volume 12 Issue 5,
September 2025
Article number: 101532
DOI: 10.1016/j.gendis.2025.101532

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Cite this article:
Zeng T, Pang J, Chong Y, et al. Sirolimus may improve bile excretion in ABCB11 mutants: A case report of a patient with bile salt export pump deficiency. Genes & Diseases, 2025, 12(5): 101532. https://doi.org/10.1016/j.gendis.2025.101532

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Received: 01 August 2024
Published: 15 January 2025
© 2025 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).