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Rapid Communication | Open Access

circFOXO3 facilitated endothelial cell senescence and atherosclerosis through binding to HnRNPK

Jing-yu Wua,b,1, Yu-lan Zhouc,1, Shui-hong Lua,b,1, Zhi-peng Yanga,b, Zhao-fu Liaoa, Dong-liang Liua, Hai-liang Moa, Yi-tuan Xied, Xinguang Liua, Xing-dong Xionga( )
Dongguan Key Laboratory of Aging and Anti-Aging, Guangdong Provincial Key Laboratory of Medical Immunology and Molecular Diagnostics, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong 523808, China
School of Medical Technology, Guangdong Medical University, Dongguan, Guangdong 523808, China
Reproductive Center, The Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524001, China
Department of Neurosurgery, Huizhou First People’s Hospital, Huizhou, Guangdong 516003, China

1 These authors shared the first authorship.

Peer review under the responsibility of the Genes & Diseases Editorial Office, in alliance with the Association of Chinese Americans in Cancer Research (ACACR, Baltimore, MD, USA).

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Genes & Diseases
Volume 12 Issue 5,
September 2025
Article number: 101517
DOI: 10.1016/j.gendis.2025.101517

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Cite this article:
Wu J-y, Zhou Y-l, Lu S-h, et al. circFOXO3 facilitated endothelial cell senescence and atherosclerosis through binding to HnRNPK. Genes & Diseases, 2025, 12(5): 101517. https://doi.org/10.1016/j.gendis.2025.101517

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Received: 10 June 2024
Published: 04 January 2025
© 2025 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).