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Rapid Communication | Open Access

GATA2 up-regulation restores androgen receptor chromatin association and advances darolutamide resistance in prostate cancer

Tianyi Zhoua, Chengtai Yua, Yali Hana, Bin Heb( ), Qin Fenga( )
Center for Nuclear Receptor and Cell Signaling, Department of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA
Immunobiology & Transplant Science Center, Department of Surgery and Urology, Houston Methodist Research Institute, Houston, TX 77030, USA

Peer review under the responsibility of the Genes & Diseases Editorial Office, in alliance with the Association of Chinese Americans in Cancer Research (ACACR, Baltimore, MD, USA).

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Genes & Diseases
Volume 12 Issue 4,
July 2025
Article number: 101508
DOI: 10.1016/j.gendis.2024.101508

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Cite this article:
Zhou T, Yu C, Han Y, et al. GATA2 up-regulation restores androgen receptor chromatin association and advances darolutamide resistance in prostate cancer. Genes & Diseases, 2025, 12(4): 101508. https://doi.org/10.1016/j.gendis.2024.101508

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Received: 03 January 2024
Published: 28 December 2024
© 2024 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).