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Rapid Communication | Open Access

IL-17 signaling pathway in SPP1+ macrophages drives digestive tract cancer progression

Yihong Weia,1, Ying Xub,1, Yanqiong Zengc, Amin Zhanga, Xiangling Xingd( ), Wancheng Liua( )
Department of Hematology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China
Eye Hospital of Shandong First Medical University, Jinan, Shandong 250012, China
National Key Laboratory of Immunity and Inflammation, Suzhou Institute of Systems Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Suzhou, Jiangsu 215123, China
Department of Radiation Oncology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China

1 These authors contributed equally to this work.

Peer review under the responsibility of the Genes & Diseases Editorial Office, in alliance with the Association of Chinese Americans in Cancer Research (ACACR, Baltimore, MD, USA)

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Genes & Diseases
Volume 12 Issue 4,
July 2025
Article number: 101489
DOI: 10.1016/j.gendis.2024.101489

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Cite this article:
Wei Y, Xu Y, Zeng Y, et al. IL-17 signaling pathway in SPP1+ macrophages drives digestive tract cancer progression. Genes & Diseases, 2025, 12(4): 101489. https://doi.org/10.1016/j.gendis.2024.101489

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Received: 25 February 2024
Published: 14 December 2024
© 2024 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).