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Rapid Communication | Open Access

Autoantigenic peptide landscape of rheumatoid arthritis-associated HLA class Ⅱ

Irina A. Ishinaa,1, Anton P. Zhiyanova,b,1, Inna N. Kurbatskaiaa,1, Azad E. Mamedova, Stepan A. Nersisyanb,2, Rustam H. Ziganshina, Igor E. Eliseeva, Yunna S. Petrusenkoa,c, Anastasia V. Nikonovaa, Elizaveta S. Zhbanovaa, Maria A. Salnikovaa,d, Leyla A. Ovchinnikovaa, Ilgar Z. Mamedova, Alexey N. Davydove,f, Kamila S. Nurbaevag, Tatiana A. Lisitsynag, Tatiana M. Reshetnyakg, Alexander M. Lilag, Evgeniy L. Nasonovg, Yakov A. Lomakina, Alexey A. Belogurov Jr.a,h, Hongkai Zhangi, Alexander G. Tonevitskiya,b, Yury P. Rubtsova( ), Alexander G. Gabibova,b,j( ), Maria Y. Zakharovaa( )
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia
Faculty of Biology and Biotechnology, Higher School of Economics, University, Moscow 117418, Russia
Biotech Campus Ltd, Moscow 117437, Russia
Institute of Translational Medicine, Pirogov Russian National Research Medical University, Moscow 117513, Russia
Central European Institute of Technology, Brno 60177, Czech Republic
MiLaboratories Inc, San Francisco, CA 94114, United States
V.A. Nasonova Research Institute of Rheumatology, Moscow 115522, Russia
Department of Biological Chemistry, Evdokimov Moscow State University of Medicine and Dentistry, Moscow 127473, Russia
State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and Frontiers Science Center for Cell Responses, Nankai University, Tianjin 300071, China
Department of Chemistry, Lomonosov Moscow State University, Moscow 119991, Russia

Peer review under the responsibility of the Genes & Diseases Editorial Office, in alliance with the Association of Chinese Americans in Cancer Research (ACACR, Baltimore, MD, USA).

1 These authors contributed equally to this work.

2 Present address: Computational Medicine Center, ThomasJefferson University, Philadelphia, PA 19107, United States.

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Genes & Diseases
Volume 12 Issue 4,
July 2025
Article number: 101469
DOI: 10.1016/j.gendis.2024.101469

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Cite this article:
Ishina IA, Zhiyanov AP, Kurbatskaia IN, et al. Autoantigenic peptide landscape of rheumatoid arthritis-associated HLA class Ⅱ. Genes & Diseases, 2025, 12(4): 101469. https://doi.org/10.1016/j.gendis.2024.101469

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Received: 12 August 2024
Published: 26 November 2024
© 2024 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).