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Rapid Communication | Open Access

ADAM8 inactivation modulates cellular component assembly gene expression in the mouse intervertebral disc

Ken Chenb,c,1, Zuozhen Tiana,1, Motomi Enomoto-Iwamotod, Yejia Zhanga,e( )
Departments of Physical Medicine & Rehabilitation, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19146, USA
School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China
Department of Orthopedics, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Section of Rehabilitation Medicine, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA

1 These authors contributed equally to this work.

Peer review under the responsibility of the Genes & Diseases Editorial Office, in alliance with the Association of Chinese Americans in Cancer Research (ACACR, Baltimore, MD, USA).

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Genes & Diseases
Volume 12 Issue 3,
May 2025
Article number: 101467
DOI: 10.1016/j.gendis.2024.101467

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Cite this article:
Chen K, Tian Z, Enomoto-Iwamoto M, et al. ADAM8 inactivation modulates cellular component assembly gene expression in the mouse intervertebral disc. Genes & Diseases, 2025, 12(3): 101467. https://doi.org/10.1016/j.gendis.2024.101467

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Received: 12 December 2023
Published: 19 November 2024
© 2024 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).