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Letter | Open Access

Runx2 controls the osteogenic fate of growth plate chondrocytes

Daofu Zenga,b,1, Jiamin Yua,b,c,1, Ke Lua,b, Dan Yia,b, Zhidao Xiad, Ling Qine, Guozhi Xiaof, Xiao Yangg, Liping Tonga( ), Di Chena,b( )
Research Center for Computer-aided Drug Discovery, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong 518055, China
Faculty of Pharmaceutical Sciences, Shenzhen University of Advanced Technology, Shenzhen, Guangdong 518055, China
University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100049, China
Institute of Life Science, Swansea University Medical School, Swansea, SA2 8PP, UK
Musculoskeletal Research Laboratory of Department of Orthopaedics & Traumatology and Innovative Orthopaedic Biomaterial & Drug Translational Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong 518172, China
School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong 518055, China
State Key Laboratory of Proteomics, Genetic Laboratory of Development and Diseases, Institute of Biotechnology, Beijing 100071, China

1 These authors contributed equally to this work.

Peer review under the responsibility of the Genes & Diseases Editorial Office, in alliance with the Association of Chinese Americans in Cancer Research (ACACR, Baltimore, MD, USA).

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Genes & Diseases
Volume 12 Issue 3,
May 2025
Article number: 101453
DOI: 10.1016/j.gendis.2024.101453

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Cite this article:
Zeng D, Yu J, Lu K, et al. Runx2 controls the osteogenic fate of growth plate chondrocytes. Genes & Diseases, 2025, 12(3): 101453. https://doi.org/10.1016/j.gendis.2024.101453

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Received: 19 February 2024
Published: 01 May 2025
© 2024 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).