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Rapid Communication | Open Access

HOXB6 down-regulation induced by retinoic acid pathway repression leads to chondrocyte proliferation inhibition and apoptosis in microtia

Run Yanga,1, Xin Chena,1, Siyi Wua,1, Chenlong Lia, Ying Chena, Yaoyao Fua, Aijuan Hea, Duan Mab( ), Jing Maa( ), Tianyu Zhanga,c( )
ENT Institute, Department of Facial Plastic and Reconstructive Surgery, Eye & ENT Hospital, Fudan University, Shanghai 200031, China
Key Laboratory of Metabolism and Molecular Medicine, Ministry of Education, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China
NHC Key Laboratory of Hearing Medicine (Fudan University), Shanghai 200031, China

Peer review under the responsibility of the Genes & Diseases Editorial Office, in alliance with the Association of Chinese Americans in Cancer Research (ACACR, Baltimore, MD, USA).

1 These authors contributed equally to this work.

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Genes & Diseases
Volume 12 Issue 3,
May 2025
Article number: 101367
DOI: 10.1016/j.gendis.2024.101367

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Cite this article:
Yang R, Chen X, Wu S, et al. HOXB6 down-regulation induced by retinoic acid pathway repression leads to chondrocyte proliferation inhibition and apoptosis in microtia. Genes & Diseases, 2025, 12(3): 101367. https://doi.org/10.1016/j.gendis.2024.101367

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Received: 18 October 2023
Published: 25 June 2024
© 2024 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).