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Rapid Communication | Open Access

In situ transcriptomic analysis of spermatocytes in non-obstructive azoospermia reveals senescence-like states in arrested spermatocytes

Zhongqin Wua,1, Xiaolong Wub,1, Zeqian Xua,1, Yixin Liua, Ziyi Zhua, Xinhui Lia, Daniel M. Czajkowskya, Fei Sunb( ), Yan Guoa( ), Zhifeng Shaoa
State Key Laboratory of Systems Medicine for Cancer, School of Biomedical Engineering and Bio-ID Center, Shanghai Jiao Tong University, Shanghai 200240, China
Department of Urology and Andrology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310016, China

1 These authors contributed equally to this work.

Peer review under responsibility of Chongqing Medical University.

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Genes & Diseases
Volume 12 Issue 1,
January 2025
Article number: 101205
DOI: 10.1016/j.gendis.2024.101205

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Cite this article:
Wu Z, Wu X, Xu Z, et al. In situ transcriptomic analysis of spermatocytes in non-obstructive azoospermia reveals senescence-like states in arrested spermatocytes. Genes & Diseases, 2025, 12(1): 101205. https://doi.org/10.1016/j.gendis.2024.101205

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Received: 09 August 2023
Published: 03 January 2024
© 2024 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).