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Rapid Communication | Open Access

Deletion of Axin1 in aggrecan-expressing cells leads to growth plate cartilage defects in adult mice

Dan Yia,b, Hongting Jinc, William W. Lub, Chunxiang Zhangd, Guozhi Xiaoe, Liping Tonga( ), Di Chena,b( )
Research Center for Computer-aided Drug Discovery, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong 518055, China
Faculty of Pharmaceutical Sciences, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong 518055, China
The First College of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China
Department of Cardiology, Basic Medicine Innovation Center for Cardiometabolic Diseases of Ministry of Education, Institute of Cardiovascular Research, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan 646000, China
School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong 518055, China

Peer review under responsibility of Chongqing Medical University.

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Genes & Diseases
Volume 11 Issue 4,
July 2024
Article number: 101147
DOI: 10.1016/j.gendis.2023.101147

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Cite this article:
Yi D, Jin H, Lu WW, et al. Deletion of Axin1 in aggrecan-expressing cells leads to growth plate cartilage defects in adult mice. Genes & Diseases, 2024, 11(4): 101147. https://doi.org/10.1016/j.gendis.2023.101147

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Received: 17 July 2023
Published: 19 October 2023
© 2024 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).