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Rapid Communication | Open Access

Epinephrine promotes tumor progression and M2 polarization of tumor-associated macrophages by regulating the TRIM2- NF-κB pathway in colorectal cancer cells

Zhengyi Liua,b,1, Chenxing Jianc,1, Wenzheng Yuand,1, Guiqing jiae, Donghui chengf, Yanzhuo Liue, Yanling Zhange, Bin Zhange, Zili Zhouc,e( ), Gaoping Zhaoe( )
Department of Breast Surgery, Henan Provincial People’s Hospital, The People’s Hospital of Zhengzhou University, The People’s Hospital of Henan University, Zhengzhou, Henan 450003, China
Microbiome Laboratory, Henan Provincia People’s Hospital Zhengzhou University People’s Hospital, Zhengzhou, Henan 450000, China
Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China
Department of Gastrointestinal Surgery II, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, China
Department of Gastrointestinal Surgery, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan 610072, China
Department of Hepatobiliary Surgery, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan 610072, China

1 These authors contributed equally to this work.

Peer review under responsibility of Chongqing Medical University.

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Genes & Diseases
Volume 11 Issue 4,
July 2024
Article number: 101092
DOI: 10.1016/j.gendis.2023.101092

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Liu Z, Jian C, Yuan W, et al. Epinephrine promotes tumor progression and M2 polarization of tumor-associated macrophages by regulating the TRIM2- NF-κB pathway in colorectal cancer cells. Genes & Diseases, 2024, 11(4): 101092. https://doi.org/10.1016/j.gendis.2023.101092

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Received: 05 November 2022
Published: 14 September 2023
© 2023 The Authors.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).