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Rapid Communication | Open Access

DLX3 (Q178R) mutation delays osteogenic differentiation via H19/miR-29c-3p/KDM5B axis in TDO-iPSCs-derived MSCs

Liying Donga,b,c,d,1, Na Zhaog,h,i,1, Dongmei Wange,1, Meng Wanga, Yixin Zhangb, Liangjie Sunb, Chong Dinga( ), Yixiang Wanga( ), Zeyun Maf( )
Central Laboratory, Peking University School and Hospital of Stomatology, Beijing 100081, China
Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, China
National Engineering Laboratory for Digital and Material Technology of Stomatology, Peking University School and Hospital of Stomatology, Beijing 100081, China
Beijing Key Laboratory of Digital Stomatology, Peking University School and Hospital of Stomatology, Beijing 100081, China
The Second Clinical Division, Peking University School and Hospital of Stomatology, Beijing 100081, China
Department of VIP Service, Peking University School and Hospital of Stomatology, Beijing 100081, China
Department of Restorative Dentistry and Biomaterials Sciences, Harvard School of Dental Medicine, Boston, MA 02115, USA
Department of Prosthodontics, Fudan University, Shanghai 200001, China
Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Shanghai Stomatological Hospital, Fudan University, Shanghai 200001, China

1 These authors contributed equally to this work.

Peer review under responsibility of Chongqing Medical University.

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Genes & Diseases
Volume 11 Issue 4,
July 2024
Article number: 101012
DOI: 10.1016/j.gendis.2023.05.011

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Dong L, Zhao N, Wang D, et al. DLX3 (Q178R) mutation delays osteogenic differentiation via H19/miR-29c-3p/KDM5B axis in TDO-iPSCs-derived MSCs. Genes & Diseases, 2024, 11(4): 101012. https://doi.org/10.1016/j.gendis.2023.05.011

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Received: 13 February 2023
Published: 03 July 2023
© 2023 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).