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Rapid Communication | Open Access

Epigenetic regulation of SARS-Cov-2 spike protein modulates cellular viability and nascent RNA transcription in neuronal cells

Xi Konga,b,1, Peng Lua,c,1, Jinyue Zhanga,b, Zheng Baoa,b, Chenghao Kuanga,b, Bingqing Xieb, Jianhua Penga,b,c, Ning Mad( ), Yong Jianga,b,c( ), Shigang Yina,b( )
Laboratory of Neurological Diseases and Brain Function, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China
Institute of Epigenetics and Brain Science, Southwest Medical University, Luzhou, Sichuan 646000, China
Department of Neurosurgery, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China
Inflammation and Allergic Diseases Research Unit, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China

1 These authors contributed equally to this work.

Peer review under responsibility of Chongqing Medical University.

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Genes & Diseases
Volume 11 Issue 2,
March 2024
Pages 535-538
DOI: 10.1016/j.gendis.2023.04.001

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Cite this article:
Kong X, Lu P, Zhang J, et al. Epigenetic regulation of SARS-Cov-2 spike protein modulates cellular viability and nascent RNA transcription in neuronal cells. Genes & Diseases, 2024, 11(2): 535-538. https://doi.org/10.1016/j.gendis.2023.04.001

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Received: 29 November 2022
Published: 08 May 2023
© 2023 The Authors.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).