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Rapid Communication | Open Access

DNA damage chemotherapeutic drugs suppress basal-like breast cancer growth by down-regulating the transcription of the FOXO1-KLF5 axis

Qiuxia Cuia,b,c,1, Jian Sunc,g,1, Jingping Yuand,1, Juanjuan Lie, Chuanyu Yangc, Guangshi Duc,f, Chengang Zhouc, Pu Qiua, Jidong Gaog,b, Yuanqi Zhanga( ), Dewei Jiangc( ), Ceshi Chenc,h,i( )
Affiliated Hospital of Guangdong Medical University Science & Technology of China, Zhanjiang, Guangdong 524000, China
Department of Breast Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/ Cancer Hospital and Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, Guangdong 518116, China
Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China
Department of Pathology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, China
Department of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, China
Translational Medicine Research Center of Guizhou Medical University, Guiyang, Guizhou 550025, China
Department of Breast Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/ Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Yunnan Cancer Hospital and the Third Affiliated Hospital of Kunming Medical University and Yunnan Cancer Center, Kunming, Yunnan 650500, China
Academy of Biomedical Engineering, Kunming Medical University, Kunming, Yunnan 650500, China

Peer review under responsibility of Chongqing Medical University.

1 These authors contributed equally to this work.

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Genes & Diseases
Volume 11 Issue 1,
January 2024
Pages 91-94
DOI: 10.1016/j.gendis.2023.03.028

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Cite this article:
Cui Q, Sun J, Yuan J, et al. DNA damage chemotherapeutic drugs suppress basal-like breast cancer growth by down-regulating the transcription of the FOXO1-KLF5 axis. Genes & Diseases, 2024, 11(1): 91-94. https://doi.org/10.1016/j.gendis.2023.03.028

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Received: 07 January 2023
Published: 02 May 2023
© 2023 The Authors.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).