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Rapid Communication | Open Access

SEMA4D acts as a novel oligogenic pathogenic gene of idiopathic hypogonadotropic hypogonadism through the PlexinB1/MET/RND1/RHOA/RAF1/MAPK signaling axis

Daoqi Wanga,b,1, Yonghua Niuc,1, Jiahong Tand, Jiaxin Wangb, Le Lingb, Yinwei Chenb, Jianan Gonge, Hao Xub, Qing Lingb, Jianhe Liua, Jihong Liub( )
Department of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650033, China
Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China
Department of Pediatric Surgery, Tongji Hospital, Tongji Medical College, Wuhan, Hubei 430030, China
Department of Obstetrics and Gynecology, The First People's Hospital of Yunnan Province, Kunming, Yunnan 650034, China
Department of Urology, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150007, China

1These authors contributed equally to this work.

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Genes & Diseases
Pages 65-68

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Wang D, Niu Y, Tan J, et al. SEMA4D acts as a novel oligogenic pathogenic gene of idiopathic hypogonadotropic hypogonadism through the PlexinB1/MET/RND1/RHOA/RAF1/MAPK signaling axis. Genes & Diseases, 2023, 10(1): 65-68. https://doi.org/10.1016/j.gendis.2022.05.030

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Published: 11 June 2022
© 2022 The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).