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Rapid Communication | Open Access

Lung adeno-squamous carcinoma modeling using oncogenic KRAS activation in human embryonic stem cell-derived alveolar organoids

Jianqi Fenga, Lian Lia, Zhihong Tana, Shanshan Zhaoa, Xin Zhanga, Jinhong Wangc, Yaping Yed, Ying Lina,f( ), Zhili Ronga,b,e,f( )
Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou, Guangdong 510515, China
Dermatology Hospital, Southern Medical University, Guangzhou, Guangdong 510091, China
Department of Respiration, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong 510630, China
Department of Pathology, Nanfang Hospital and School of Basic Medical Science, Southern Medical University, Guangzhou, Guangdong 510515, China
Bioland Laboratory (Guangzhou Regenerative Medicine and Health Guangdong Laboratory), Guangzhou, Guangdong 510005, China
Experimental Education/Administration Center, School of Basic Medical Science, Southern Medical University, Guangzhou, Guangdong 510515, China
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Genes & Diseases
Volume 10 Issue 1,
January 2023
Pages 33-36
DOI: 10.1016/j.gendis.2022.03.015

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Cite this article:
Feng J, Li L, Tan Z, et al. Lung adeno-squamous carcinoma modeling using oncogenic KRAS activation in human embryonic stem cell-derived alveolar organoids. Genes & Diseases, 2023, 10(1): 33-36. https://doi.org/10.1016/j.gendis.2022.03.015

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Published: 07 April 2022
© 2022 The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).