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Dendritic mesoporous silica nanoparticles (DMSNs) are a new class of solid porous materials used for enzyme immobilization support due to their intrinsic characteristics, including their unique open central–radial structures with large pore channels and their excellent biocompatibility. In this review, we review the recent progress in research on enzyme immobilization using DMSNs with different structures, namely, flower-like DMSNs and tree-branch-like DMSNs. Three DMSN synthesis methods are briefly compared, and the distinct characteristics of the two DMSN types and their effects on the catalytic performance of immobilized enzymes are comprehensively discussed. Possible directions for future research on enzyme immobilization using DMSNs are also proposed.
This work was supported by the National Natural Science Foundation of China (No. 22178083), the Natural Science Foundation of Hebei Province (C2019208174 and B2022202014), the S&T Program of Hebei (20372802D, 21372804D, and 21372805D), and the Natural Science Foundation of Tianjin City (20JCYBJC00530).
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).