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Food Science and Human Wellness 2018, 7(2): 120-124 https://doi.org/10.1016/j.fshw.2018.05.001
Research Article | Open Access | Issue | Published: 19 June 2018

The effects of the extract of oolong tea and its metabolites from Andraca theae in high fat diet induced obese Wistar rat

Show Author's Information Yen-Chen Tunga,1,  Tsung-Hai Hsieha,1,  Meei-Ju Yangb,  Wei-Lun Hungc,  Chi-Tang Hod,  Min-Hsiung Pana( )
Institute of Food Science and Technology, National Taiwan University, Taipei 106, Taiwan, China
Tea Research and Extension Station, Taoyuan 326, Taiwan, China
Citrus Research and Education Center, Department of Food Science and Human Nutrition, University of Florida, Lake Alfred, FL, 33850, USA
Department of Food Science, Rutgers University, New Brunswick, NJ 08901, USA

1 The authors contributed this work equally.

Peer review under responsibility of KeAi Communications Co., Ltd.

Keywords:
Obesity, High fat diet, Tea, Andraca theae
Cite this article:
Tung Y-C, Hsieh T-H, Yang M-J, et al. The effects of the extract of oolong tea and its metabolites from Andraca theae in high fat diet induced obese Wistar rat. Food Science and Human Wellness, 2018, 7(2): 120-124. https://doi.org/10.1016/j.fshw.2018.05.001
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Abstract Full text About this article

Obesity is a critical health issue worldwide. For a long time, the concept of drinking tea for health and pleasure is widely accepted. The strain of Andraca theae lives on the tea leaf and the bioactivity of its metabolites in the feces is unknown yet. Thus, the objective of this study was to investigate whether the extract of tea (Taiwan Tea Experiment Station No.12 (TE)) and its metabolites from Andraca theae (TME) could prevent obesity in the high fat diet-induced obese rats. Our results showed that TE had higher concentrations of epigallocatechin gallate (EGCG) and caffeine than that from TME. TE significantly decreased abdominal adipose tissue, especially epididymal fat via increasing preadipocyte factor 1 (Pref-1), SRY (sex determining region Y)-box 9 (SOX-9) and decreasing peroxisome proliferator-activated receptor γ (PPARγ), CCAAT/enhancer binding protein (C/EBP)β, C/EBPα and C/EBPγ protein expression. Taken together, these results suggest that the content of tea polyphenols in TE play an important role for alleviating abdominal fat.


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About this article

The effects of the extract of oolong tea and its metabolites from Andraca theae in high fat diet induced obese Wistar rat

Show Author's information Yen-Chen Tunga,1, Tsung-Hai Hsieha,1, Meei-Ju Yangb, Wei-Lun Hungc, Chi-Tang Hod, Min-Hsiung Pana( )
Institute of Food Science and Technology, National Taiwan University, Taipei 106, Taiwan, China
Tea Research and Extension Station, Taoyuan 326, Taiwan, China
Citrus Research and Education Center, Department of Food Science and Human Nutrition, University of Florida, Lake Alfred, FL, 33850, USA
Department of Food Science, Rutgers University, New Brunswick, NJ 08901, USA

1 The authors contributed this work equally.

Peer review under responsibility of KeAi Communications Co., Ltd.

Abstract

Obesity is a critical health issue worldwide. For a long time, the concept of drinking tea for health and pleasure is widely accepted. The strain of Andraca theae lives on the tea leaf and the bioactivity of its metabolites in the feces is unknown yet. Thus, the objective of this study was to investigate whether the extract of tea (Taiwan Tea Experiment Station No.12 (TE)) and its metabolites from Andraca theae (TME) could prevent obesity in the high fat diet-induced obese rats. Our results showed that TE had higher concentrations of epigallocatechin gallate (EGCG) and caffeine than that from TME. TE significantly decreased abdominal adipose tissue, especially epididymal fat via increasing preadipocyte factor 1 (Pref-1), SRY (sex determining region Y)-box 9 (SOX-9) and decreasing peroxisome proliferator-activated receptor γ (PPARγ), CCAAT/enhancer binding protein (C/EBP)β, C/EBPα and C/EBPγ protein expression. Taken together, these results suggest that the content of tea polyphenols in TE play an important role for alleviating abdominal fat.

Keywords: Obesity, High fat diet, Tea, Andraca theae

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Publication history

Received: 10 April 2018
Accepted: 28 April 2018
Published: 19 June 2018
Issue date: June 2018

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© 2018 “Society information”.

Acknowledgements

Acknowledgment

This study was supported by the Ministry of Science and Technology [105-2320-B-002-031-MY3, 105-2628-B-002-003-MY3].

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This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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