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Food Science and Human Wellness 2015, 4(2): 56-65 https://doi.org/10.1016/j.fshw.2015.06.002
Research Article | Open Access | Issue | Published: 21 June 2015

New perspectives on probiotics in health and disease

Show Author's Information Eric Banan-Mwine Daliria,  Byong H. Leea,b,c( )
School of Biotechnology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China
Department of Food Science and Biotechnology, Kangwon National University, Chuncheon 200-701, South Korea
Department of Food Science/Agricultural Chemistry, McGill University, Ste-Anne-de-Bellevue, QC, Canada H9X 3V9

Peer review under responsibility of Beijing Academy of Food Sciences.

Keywords:
Microbiome, Probiotic, Dysbiosis, Heath benefits, Bile salt hydrolase
Cite this article:
Daliri EB-M, Lee BH. New perspectives on probiotics in health and disease. Food Science and Human Wellness, 2015, 4(2): 56-65. https://doi.org/10.1016/j.fshw.2015.06.002
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Abstract Full text About this article

The gut microbiota continues to fascinate scientists in many realms when it is considered that humans contain 90% bacteria. Correlations between changes in composition and activity of the gut microbiota and common disorders such as cancer, hypertension, hypercholesterolemia, inflammatory bowel diseases, obesity, oral health, etc. have been proposed. What is the real role of probiotics, prebiotics and synbiotics in influencing a healthy microbiota? Both in vitro evidences and in vivo clinical data have supported some of these new health claims, while recent molecular advancement has provided strong indications to support and justify the hypotheses. However, probiotics validity and health claims have continuously been rejected on the basis of “biomarker deficiency”. To battle the increase in health care costs, a preventive approach to medicine with the development of probiotics and prebiotics or symbiotic products is being advanced. This review discusses the potential beneficial effects of probiotics in preventing and treating certain diseases as well as current and future perspectives of probiotic research.


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About this article

New perspectives on probiotics in health and disease

Show Author's information Eric Banan-Mwine Daliria, Byong H. Leea,b,c( )
School of Biotechnology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China
Department of Food Science and Biotechnology, Kangwon National University, Chuncheon 200-701, South Korea
Department of Food Science/Agricultural Chemistry, McGill University, Ste-Anne-de-Bellevue, QC, Canada H9X 3V9

Peer review under responsibility of Beijing Academy of Food Sciences.

Abstract

The gut microbiota continues to fascinate scientists in many realms when it is considered that humans contain 90% bacteria. Correlations between changes in composition and activity of the gut microbiota and common disorders such as cancer, hypertension, hypercholesterolemia, inflammatory bowel diseases, obesity, oral health, etc. have been proposed. What is the real role of probiotics, prebiotics and synbiotics in influencing a healthy microbiota? Both in vitro evidences and in vivo clinical data have supported some of these new health claims, while recent molecular advancement has provided strong indications to support and justify the hypotheses. However, probiotics validity and health claims have continuously been rejected on the basis of “biomarker deficiency”. To battle the increase in health care costs, a preventive approach to medicine with the development of probiotics and prebiotics or symbiotic products is being advanced. This review discusses the potential beneficial effects of probiotics in preventing and treating certain diseases as well as current and future perspectives of probiotic research.

Keywords: Microbiome, Probiotic, Dysbiosis, Heath benefits, Bile salt hydrolase

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Publication history
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Publication history

Received: 07 April 2015
Revised: 11 May 2015
Accepted: 08 June 2015
Published: 21 June 2015
Issue date: June 2015

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© 2015 Beijing Academy of Food Sciences.

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