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Review | Open Access

Recent advances in the construction of nanozyme-based logic gates

Fang Pu1, Jinsong Ren1,2, Xiaogang Qu1,2( )
Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China
University of Science and Technology of China, Hefei 230026, China
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Abstract

Nanozymes, nanomaterials with enzyme-like activity, have been considered as promising alternatives of natural enzymes. Molecular logic gates, which can simulate the function of the basic unit of an electronic computer, perform Boolean logic operation in response to chemical, biological, or optical signals. Recently, the combination of nanozymes and logic gates enabled bioinformation processing in a logically controllable way. In the review, recent progress in the construction of nanozyme-based logic gates integrated with their utility in sensing is introduced. Furthermore, the issues and challenges in the construction processes are discussed. It is expected the review will facilitate a comprehensive understanding of nanozyme-based logic systems.

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Keywords

NanozymeLogic gateSensorRegulationInput

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Biophysics Reports
Volume 6 Issue 6,
December 2020
Pages 245-255
DOI: 10.1007/s41048-020-00124-9

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Pu F, Ren J, Qu X. Recent advances in the construction of nanozyme-based logic gates. Biophysics Reports, 2020, 6(6): 245-255. https://doi.org/10.1007/s41048-020-00124-9

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Received: 28 June 2020
Accepted: 15 October 2020
Published: 21 November 2020
© The Author(s) 2020

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