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Biophysics Reports 2020, 6(6): 245-255 https://doi.org/10.1007/s41048-020-00124-9
Review | Open Access | Issue | Published: 21 November 2020

Recent advances in the construction of nanozyme-based logic gates

Show Author's Information Fang Pu1,  Jinsong Ren1,2,  Xiaogang Qu1,2( )
Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China
University of Science and Technology of China, Hefei 230026, China
Keywords:
Logic gate, Sensor, Nanozyme, Regulation, Input
Cite this article:
Pu F, Ren J, Qu X. Recent advances in the construction of nanozyme-based logic gates. Biophysics Reports, 2020, 6(6): 245-255. https://doi.org/10.1007/s41048-020-00124-9
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Abstract Full text About this article

Nanozymes, nanomaterials with enzyme-like activity, have been considered as promising alternatives of natural enzymes. Molecular logic gates, which can simulate the function of the basic unit of an electronic computer, perform Boolean logic operation in response to chemical, biological, or optical signals. Recently, the combination of nanozymes and logic gates enabled bioinformation processing in a logically controllable way. In the review, recent progress in the construction of nanozyme-based logic gates integrated with their utility in sensing is introduced. Furthermore, the issues and challenges in the construction processes are discussed. It is expected the review will facilitate a comprehensive understanding of nanozyme-based logic systems.


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About this article

Recent advances in the construction of nanozyme-based logic gates

Show Author's information Fang Pu1, Jinsong Ren1,2, Xiaogang Qu1,2( )
Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China
University of Science and Technology of China, Hefei 230026, China

Abstract

Nanozymes, nanomaterials with enzyme-like activity, have been considered as promising alternatives of natural enzymes. Molecular logic gates, which can simulate the function of the basic unit of an electronic computer, perform Boolean logic operation in response to chemical, biological, or optical signals. Recently, the combination of nanozymes and logic gates enabled bioinformation processing in a logically controllable way. In the review, recent progress in the construction of nanozyme-based logic gates integrated with their utility in sensing is introduced. Furthermore, the issues and challenges in the construction processes are discussed. It is expected the review will facilitate a comprehensive understanding of nanozyme-based logic systems.

Keywords: Logic gate, Sensor, Nanozyme, Regulation, Input

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Publication history

Received: 28 June 2020
Accepted: 15 October 2020
Published: 21 November 2020
Issue date: December 2020

Copyright

© The Author(s) 2020

Acknowledgements

Acknowledgements

Studies in our laboratory were aided by the National Key R&D Program of China (2019YFA0709202), National Natural Science Foundation of China (21533008, 21871249, 91856205, 21673223, 21977091 and 21820102009), and Key Program of Frontier of Sciences (CAS QYZDJ-SSW-SLH052).

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