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Alkoxysilane precursors are the most widely used silica source for sol–gel preparation of silicate-based bioactive glass. However, due to their high cost, alternative sources such as bentonite clay are desirable. In the present work, bentonite clay was reacted with sodium hydroxide (NaOH) to extract sodium metasilicate (Na2SiO3). The obtained Na2SiO3 was converted to gel which was then sintered at 950 ℃ for 3 h to give the bioactive glass in the quaternary composition SiO2–NaO–CaO– P2O5. The resulting glass was incubated in simulated body fluid (SBF) for 0–7 days to evaluate the bioactivity. Furthermore, glass samples were characterized before and after SBF study by scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR). Results obtained showed the presence of Na2Ca2Si3O9 (combeite) crystal as the major crystalline phase and the formation of hydroxyapatite (HA) and hydroxycarbonated apatite (HCA) on the surface of the glass after immersion in SBF. The material showed potentials for application as scaffold in bone tissue repair.


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Bioactivity of quaternary glass prepared from bentonite clay

Show Author's information Luqman A. ADAMSa( )Enobong R. ESSIENb
Department of Chemistry, University of Lagos, Nigeria
Department of Chemical Sciences, Bells University of Technology, P.M.B 1015 Ota, Ogun, Nigeria

Abstract

Alkoxysilane precursors are the most widely used silica source for sol–gel preparation of silicate-based bioactive glass. However, due to their high cost, alternative sources such as bentonite clay are desirable. In the present work, bentonite clay was reacted with sodium hydroxide (NaOH) to extract sodium metasilicate (Na2SiO3). The obtained Na2SiO3 was converted to gel which was then sintered at 950 ℃ for 3 h to give the bioactive glass in the quaternary composition SiO2–NaO–CaO– P2O5. The resulting glass was incubated in simulated body fluid (SBF) for 0–7 days to evaluate the bioactivity. Furthermore, glass samples were characterized before and after SBF study by scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR). Results obtained showed the presence of Na2Ca2Si3O9 (combeite) crystal as the major crystalline phase and the formation of hydroxyapatite (HA) and hydroxycarbonated apatite (HCA) on the surface of the glass after immersion in SBF. The material showed potentials for application as scaffold in bone tissue repair.

Keywords:

bentonite clay, bioactivity, alkoxysilane, hydroxyapatite (HA), bone repair
Received: 27 July 2015 Revised: 15 September 2015 Accepted: 14 October 2015 Published: 07 January 2016 Issue date: June 2021
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Publication history
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Publication history

Received: 27 July 2015
Revised: 15 September 2015
Accepted: 14 October 2015
Published: 07 January 2016
Issue date: June 2021

Copyright

© The author(s) 2016

Acknowledgements

The authors are thankful to Mr. Femi Igbari of the College of NanoScience and Technology, Soochow University, China, for his assistance with the EDX and XRD characterisations as well as Mr. Isa Yakubu of Ahmadu Bello University Zaria for the SEM analysis.

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