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The aim of this work was to study the influence of the different synthesis processes on microstructural and morphological characteristics and distribution of hydroxyapatite-bioactive glass (HAp-BG) composite nanopowders obtained by sol–gel method. HAp-BG composite nanopowders with 20 wt% bioactive glass were prepared using a sol–gel method via four routes: (I) mixing the prepared HAp solution with BG solution before aging time; (II) mixing the prepared BG solution with the prepared HAp gel after gelation; (III) mixing the calcined BG nanopowders with the prepared HAp solution; and (IV) mixing the two prepared calcined nanopowders by mechanochemical activation. The prepared nanopowders were evaluated and studied by X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray spectrometer (EDS), Fourier transform infrared (FTIR), transmission electron diffraction (TEM) and Brunauer–Emmet–Teller (BET) method to investigate the phase structure, microstructure and morphology, functional groups, and the size and distribution of nanopowders. Results indicated that morphology, crystallinity, crystallite size and specific surface area (SSA) of the powders are highly correspondent to the process and type of synthesis method. These findings suggest that the modified sol–gel derived HAp-BG composite nanopowders are expected to efficiently provide a possibility to produce a good candidate to use for fabrication of a bulk nanostructured HAp-BG composite for bone tissue engineering.


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Effect of different sol–gel synthesis processes on microstructural and morphological characteristics of hydroxyapatite-bioactive glass composite nanopowders

Show Author's information Mohamadhassan TAHERIANa,b( )Ramin ROJAEEb,cMohammadhossein FATHIb,cMorteza TAMIZIFARa
Department of Materials and Metallurgical Engineering, Iran University of Science and Technology (IUST), Tehran 16866-13114, Iran
Biomaterials Research Group, Department of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran
Dental Materials Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

The aim of this work was to study the influence of the different synthesis processes on microstructural and morphological characteristics and distribution of hydroxyapatite-bioactive glass (HAp-BG) composite nanopowders obtained by sol–gel method. HAp-BG composite nanopowders with 20 wt% bioactive glass were prepared using a sol–gel method via four routes: (I) mixing the prepared HAp solution with BG solution before aging time; (II) mixing the prepared BG solution with the prepared HAp gel after gelation; (III) mixing the calcined BG nanopowders with the prepared HAp solution; and (IV) mixing the two prepared calcined nanopowders by mechanochemical activation. The prepared nanopowders were evaluated and studied by X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray spectrometer (EDS), Fourier transform infrared (FTIR), transmission electron diffraction (TEM) and Brunauer–Emmet–Teller (BET) method to investigate the phase structure, microstructure and morphology, functional groups, and the size and distribution of nanopowders. Results indicated that morphology, crystallinity, crystallite size and specific surface area (SSA) of the powders are highly correspondent to the process and type of synthesis method. These findings suggest that the modified sol–gel derived HAp-BG composite nanopowders are expected to efficiently provide a possibility to produce a good candidate to use for fabrication of a bulk nanostructured HAp-BG composite for bone tissue engineering.

Keywords:

hydroxyapatite (HAp), bioactive glass (BG), composite, nanopowders, sol–gel
Received: 15 March 2014 Revised: 31 May 2014 Accepted: 06 June 2014 Published: 02 September 2014 Issue date: September 2014
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Publication history

Received: 15 March 2014
Revised: 31 May 2014
Accepted: 06 June 2014
Published: 02 September 2014
Issue date: September 2014

Copyright

© The author(s) 2014

Acknowledgements

This work was supported by Biomaterials Research Group of Isfahan University of Technology, Iran.

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