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Research Article | Online First

Large-scale manufacturing of functional single-atom ink for convenient glucose sensing

Muyu Yan1,2Xiaofei Zhu1,2Can Xiong4Xiao Han4Zhenggang Xue3( )Yuen Wu1,2( )
Department of Endocrinology, Institute of Endocrine and Metabolic Diseases, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China
Deep Space Exploration Laboratory, University of Science and Technology of China, Hefei 230026, China
NEST Laboratory, Department of Physics, Department of Chemistry, College of Science, Shanghai University, Shanghai 200444, China
Center of Advanced Nanocatalysis (CAN), Department of Applied Chemistry, University of Science and Technology of China, Hefei 230026, China
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Abstract

Printing techniques hold great potential in the manufacture of electronics such as sensors, micro-supercapacitors, and flexible electronics. However, developing large-scale functional conductive inks with appropriate rheological properties and active components still remains a challenge. Herein, through optimizing the formulations of ink, iron single sites supported N-doped carbon black (Fe1-NC) inks can serve as both conductive electrodes and high-reactive catalysts to realize convenient glucose detection, which pronouncedly reduces the dosage of enzyme and simplifies the sensors preparation. In detail, utilizing in-situ pyrolysis method, Fe1-NC single-atom catalysts (SACs) are prepared in bulk (dekagram-level). The batched Fe1-NC SACs materials can be uniformly mixed with modulated ink to realize the screen printing with high resolution and uniformity. Also, the whole scalable preparation and ink-functional process can be extended to various metals (including Co, Ni, Cu, and Mn). The introduction of highly active Fe1-NC sites reduces the amount of enzyme used in glucose detection by at least 50%, contributing to the cost reduction of sensors. The strategy in harnessing the SACs onto the carbon inks thus provides a broad prospect for the low-cost and large-scale printing of sensitive sensing devices.

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Nano Research
Cite this article:
Yan M, Zhu X, Xiong C, et al. Large-scale manufacturing of functional single-atom ink for convenient glucose sensing. Nano Research, 2024, https://doi.org/10.1007/s12274-024-6702-6
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Received: 29 February 2024
Revised: 10 April 2024
Accepted: 11 April 2024
Published: 16 May 2024
© Tsinghua University Press 2024
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