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Research Article

A time sequential microfluid sensor with Tesla valve channels

Pengcheng Zhao1Haobin Wang1Yaozheng Wang1Wei Zhao2Mengdi Han3Haixia Zhang1( )
National Key Laboratory of Science and Technology on Micro/Nano Fabrication, Beijing Advanced Innovation Center for Integrated Circuits, School of Integrated Circuits, Peking University, Beijing 100871, China
Department of Cardiology and Institute of Vascular Medicine, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing Key Laboratory of Cardiovascular Receptors Research, Peking University Third Hospital, Beijing 100191, China
Department of Biomedical Engineering College of Future Technology, Peking University, Beijing 100871, China
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Abstract

The concentration of biomarkers in sweat can be used to evaluate human health, making efficient sweat sensing a focus of research. While flow channel design is often used to detect sweat velocity, it is rarely incorporated into the sensing of biomarkers, limiting the richness of sensing results. In this study, we report a time sequential sensing scheme for uric acid in sweat through a sequential design of Tesla valve channels. Graphene electrodes for detecting uric acid and directional Tesla valve flow channels were fabricated using laser engraving technology to realize time sequential sensing. The performance of the channels was verified through simulation. The time sequential detection of uric acid concentration in sweat can help researchers improve the establishment of human health management systems through flexible wearable devices.

Graphical Abstract

We designed a wearable time sequential sweat uric acid microfluid sensor with Tesla valve channels and fabricated the patch with laser process.

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Nano Research
Pages 11667-11673

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Cite this article:
Zhao P, Wang H, Wang Y, et al. A time sequential microfluid sensor with Tesla valve channels. Nano Research, 2023, 16(9): 11667-11673. https://doi.org/10.1007/s12274-023-5778-8
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Received: 31 January 2023
Revised: 06 April 2023
Accepted: 25 April 2023
Published: 27 May 2023
© Tsinghua University Press 2023