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Nano Research 2023, 16(4): 5401-5411 https://doi.org/10.1007/s12274-022-5107-7
Research Article | Issue | Published: 09 November 2022

Multifunctional N,S-doped and methionine functionalized carbon dots for on−off−on Fe3+ and ascorbic acid sensing, cell imaging, and fluorescent ink applying

Show Author's Information Zheng Yang1,2,3,  Tiantian Xu2,  Shaobing Zhang2,  Hui Li1,2,  Yali Ji1,  Xiaodan Jia2,3,  Jianli Li1( )
Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry & Materials Science, Northwest University, Xi’an 710127, China
College of Chemistry and Chemical Engineering, Xi’an University of Science and Technology, Xi’an 710054, China
Key Laboratory of Coal Resources Exploration and Comprehensive Utilization, Ministry of Land and Resources, Xi’an 710012, China
Keywords:
carbon dots, ascorbic acid, fluorescent sensors, Fe3+, fluorescent ink, message encryption
Topics:
Fluorescence imaging
Cite this article:
Yang Z, Xu T, Zhang S, et al. Multifunctional N,S-doped and methionine functionalized carbon dots for on−off−on Fe3+ and ascorbic acid sensing, cell imaging, and fluorescent ink applying. Nano Research, 2023, 16(4): 5401-5411. https://doi.org/10.1007/s12274-022-5107-7
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CSCD

Abstract Full text Electronic supplementary material About this article

Fluorescent carbon dots (CDs) have been identified as potential nanosensors and attracted tremendous research interests in wide areas including anti-counterfeiting, environmental and biological sensing and imaging in considering of the attractive optical properties. In this work, we present a CDs based fluorescent sensor from polyvinylpyrrolidone, citric acid, and methionine as precursors by hydrothermal approach. The selective quantifying of Fe3+ and ascorbic acid (AA) are based on the fluorescent on–off–on process, in which the fluorescent quenching is induced by the coordination of the Fe3+ on the surface of the CDs, while the fluorescence recovery is mainly attributed to redox reaction between Fe3+ and AA, breaking the coordination and bringing the fluorescence back. Inspired by the good water solubility and biocompatibility, significant photostability, superior photobleaching resistance as well as high selectivity, sensitivity, and interference immunity, which are constructed mainly from the N,S-doping and methionine surface functionalization, the CDs have not only been employed as fluorescence ink in multiple anti-counterfeiting printing and confidential document writing or transmitting, but also been developed as promising fluorescence sensors in solution and solid by CDs doped test strips and hydrogels for effectively monitoring and removing of Fe3+ and AA in environmental aqueous solution. The CDs have been also implemented as effective diagnostic candidates for imaging and tracking of Fe3+ and AA in living cells, accelerating the understanding of their function and importance in related biological processes for the prevention and treatment specific diseases.


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Abstract
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Electronic supplementary material
About this article

Multifunctional N,S-doped and methionine functionalized carbon dots for on−off−on Fe3+ and ascorbic acid sensing, cell imaging, and fluorescent ink applying

Show Author's information Zheng Yang1,2,3, Tiantian Xu2, Shaobing Zhang2, Hui Li1,2, Yali Ji1, Xiaodan Jia2,3, Jianli Li1( )
Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry & Materials Science, Northwest University, Xi’an 710127, China
College of Chemistry and Chemical Engineering, Xi’an University of Science and Technology, Xi’an 710054, China
Key Laboratory of Coal Resources Exploration and Comprehensive Utilization, Ministry of Land and Resources, Xi’an 710012, China

Abstract

Fluorescent carbon dots (CDs) have been identified as potential nanosensors and attracted tremendous research interests in wide areas including anti-counterfeiting, environmental and biological sensing and imaging in considering of the attractive optical properties. In this work, we present a CDs based fluorescent sensor from polyvinylpyrrolidone, citric acid, and methionine as precursors by hydrothermal approach. The selective quantifying of Fe3+ and ascorbic acid (AA) are based on the fluorescent on–off–on process, in which the fluorescent quenching is induced by the coordination of the Fe3+ on the surface of the CDs, while the fluorescence recovery is mainly attributed to redox reaction between Fe3+ and AA, breaking the coordination and bringing the fluorescence back. Inspired by the good water solubility and biocompatibility, significant photostability, superior photobleaching resistance as well as high selectivity, sensitivity, and interference immunity, which are constructed mainly from the N,S-doping and methionine surface functionalization, the CDs have not only been employed as fluorescence ink in multiple anti-counterfeiting printing and confidential document writing or transmitting, but also been developed as promising fluorescence sensors in solution and solid by CDs doped test strips and hydrogels for effectively monitoring and removing of Fe3+ and AA in environmental aqueous solution. The CDs have been also implemented as effective diagnostic candidates for imaging and tracking of Fe3+ and AA in living cells, accelerating the understanding of their function and importance in related biological processes for the prevention and treatment specific diseases.

Keywords: carbon dots, ascorbic acid, fluorescent sensors, Fe3+, fluorescent ink, message encryption

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Publication history
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Acknowledgements

Publication history

Received: 08 August 2022
Revised: 19 September 2022
Accepted: 26 September 2022
Published: 09 November 2022
Issue date: April 2023

Copyright

© Tsinghua University Press 2022

Acknowledgements

Acknowledgements

This work is supported by the National Natural Science Foundation of China (Nos. 22171223, 22179107, 22077099, and 21807087), the Technology Innovation Leading Program of Shaanxi (No. 2020TG−031), the Shaanxi Provincial Natural Science Fund Project (No. 2018JQ2061), the Xi’an City Science and Technology Project (Nos. 2020KJRC011 and 2019218214GXRC018CG019−GXYD18.4), and the Outstanding Youth Science Fund of Xi’an University of Science and Technology (No. 2018YQ3–14).

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