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Nano Research 2022, 15(6): 5245-5255 https://doi.org/10.1007/s12274-022-4136-6
Research Article | Issue | Published: 09 March 2022

A sprayable superhydrophobic dental protectant with photo-responsive anti-bacterial, acid-resistant, and anti-fouling functions

Show Author's Information Siyu Zhao1,2,3,§,  Xuetao Yang1,2,§,  Yingying Xu1,3,  Zhenzhen Weng4,  Lan Liao1,3( ),  Xiaolei Wang2,4( )
The Affiliated Stomatological Hospital, Nanchang University, Nanchang 330006, China
The National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Nanchang University, Nanchang 330088, China
The Key Laboratory of Oral Biomedicine, Nanchang 330006, China
College of Chemistry, Nanchang University, Nanchang 330088, China

§ Siyu Zhao and Xuetao Yang contributed equally to this work.

Keywords:
photocatalysis, ZnO, superhydrophobicity, antibacterial, dental membrane
Topics:
Nano biology
Cite this article:
Zhao S, Yang X, Xu Y, et al. A sprayable superhydrophobic dental protectant with photo-responsive anti-bacterial, acid-resistant, and anti-fouling functions. Nano Research, 2022, 15(6): 5245-5255. https://doi.org/10.1007/s12274-022-4136-6
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Abstract Full text Electronic supplementary material About this article

Effective dental care can reduce the incidence of oral diseases (dental caries, dentin sensitivity, tooth discoloration, etc.). However, delayed or inappropriate usage of care tools not only fails to eliminate external adverse stimuli, but sometimes even causes dental injury. Inspired by the traditional culture of “lacquer teeth”, a sprayable superhydrophobic protectant (ZFP) composed of ZnO, fluorine modified nano-silica (FSNs), and polydimethylsiloxane (PDMS) is constructed similar to automobile wax, for routine dental protection. With its superhydrophobic properties, this protective membrane can effectively resist the adhesion of bacteria, proteins, and food residues to the teeth surface. Meanwhile, ZFP exerts stable superhydrophobic self-cleaning properties under external mechanical stimulation, temperature alternation, and acidic environment. In addition, ZnO in ZFP can significantly restrain the growth of dental caries-related bacteria (Streptococcus mutans), with an enhanced anti-bacterial capacity when combined with yellow light irradiation. Both in vivo and in vitro experiments demonstrate that ZFP is a safe, convenient, and quadruplex-effective dental protectant, which is expected to serve as a promising toothpaste companion for joint maintenance of dental health.


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Electronic supplementary material
About this article

A sprayable superhydrophobic dental protectant with photo-responsive anti-bacterial, acid-resistant, and anti-fouling functions

Show Author's information Siyu Zhao1,2,3,§, Xuetao Yang1,2,§, Yingying Xu1,3, Zhenzhen Weng4, Lan Liao1,3( ), Xiaolei Wang2,4( )
The Affiliated Stomatological Hospital, Nanchang University, Nanchang 330006, China
The National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Nanchang University, Nanchang 330088, China
The Key Laboratory of Oral Biomedicine, Nanchang 330006, China
College of Chemistry, Nanchang University, Nanchang 330088, China

§ Siyu Zhao and Xuetao Yang contributed equally to this work.

Abstract

Effective dental care can reduce the incidence of oral diseases (dental caries, dentin sensitivity, tooth discoloration, etc.). However, delayed or inappropriate usage of care tools not only fails to eliminate external adverse stimuli, but sometimes even causes dental injury. Inspired by the traditional culture of “lacquer teeth”, a sprayable superhydrophobic protectant (ZFP) composed of ZnO, fluorine modified nano-silica (FSNs), and polydimethylsiloxane (PDMS) is constructed similar to automobile wax, for routine dental protection. With its superhydrophobic properties, this protective membrane can effectively resist the adhesion of bacteria, proteins, and food residues to the teeth surface. Meanwhile, ZFP exerts stable superhydrophobic self-cleaning properties under external mechanical stimulation, temperature alternation, and acidic environment. In addition, ZnO in ZFP can significantly restrain the growth of dental caries-related bacteria (Streptococcus mutans), with an enhanced anti-bacterial capacity when combined with yellow light irradiation. Both in vivo and in vitro experiments demonstrate that ZFP is a safe, convenient, and quadruplex-effective dental protectant, which is expected to serve as a promising toothpaste companion for joint maintenance of dental health.

Keywords: photocatalysis, ZnO, superhydrophobicity, antibacterial, dental membrane

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Publication history
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Acknowledgements

Publication history

Received: 04 November 2021
Revised: 03 January 2022
Accepted: 04 January 2022
Published: 09 March 2022
Issue date: June 2022

Copyright

© Tsinghua University Press 2022

Acknowledgements

Acknowledgements

This work was funded by the National Natural Science Foundation of China (No. 31860263 to X. L. W. and and No. 81960492 to L. L.), Key Youth Project of Jiangxi Province (No. 20202ACB216002 to X. L. W.), Natural Science Foundation of Jiangxi Province (No. S2018ZRZDB0255 to L. L.), and Nanchang University Seed Grant for Biomedicine.

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