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Fully rubbery synaptic transistors made out of all-organic materials for elastic neurological electronic skin
Cunjiang Yu1,4,5,6,7(
)
)Abstract
Neurologic function implemented soft organic electronic skin holds promise for wide range of applications, such as skin prosthetics, neurorobot, bioelectronics, human-robotic interaction (HRI), etc. Here, we report the development of a fully rubbery synaptic transistor which consists of all-organic materials, which shows unique synaptic characteristics existing in biological synapses. These synaptic characteristics retained even under mechanical stretch by 30%. We further developed a neurological electronic skin in a fully rubbery format based on two mechanoreceptors (for synaptic potentiation or depression) of pressure-sensitive rubber and an all-organic synaptic transistor. By converting tactile signals into Morse Code, potentiation and depression of excitatory postsynaptic current (EPSC) signals allow the neurological electronic skin on a human forearm to communicate with a robotic hand. The collective studies on the materials, devices, and their characteristics revealed the fundamental aspects and applicability of the all-organic synaptic transistor and the neurological electronic skin.
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References
1
Thompson, W. Synapse elimination in neonatal rat muscle is sensitive to pattern of muscle use. Nature 1983, 302, 614–616.
2
Chortos, A.; Liu, J.; Bao, Z. N. Pursuing prosthetic electronic skin. Nat. Mater. 2016, 15, 937–950.
3
Shim, H.; Sim, K.; Ershad, F.; Yang, P. Y.; Thukral, A.; Rao, Z. Y.; Kim, H. J.; Liu, Y. H.; Wang, X.; Gu, G. Y. et al. Stretchable elastic synaptic transistors for neurologically integrated soft engineering systems. Sci. Adv. 2019, 5, eaax4961.
4
Zhu, L. Q.; Wan, C. J.; Guo, L. Q.; Shi, Y.; Wan, Q. Artificial synapse network on inorganic proton conductor for neuromorphic systems. Nat. Commun. 2014, 5, 3158.
5
Andreae, L. C.; Burrone, J. The role of spontaneous neurotransmission in synapse and circuit development. J. Neurosci. Res. 2018, 96, 354–359.
6
Kim, S.; Lee, B.; Reeder, J. T.; Seo, S. H.; Lee, S. U.; Hourlier- Fargette, A.; Shin, J.; Sekine, Y.; Jeong, H.; Oh, Y. S. et al. Soft, skin-interfaced microfluidic systems with integrated immunoassays, fluorometric sensors, and impedance measurement capabilities. Proc. Natl. Acad. Sci. USA 2020, 117, 27906–27915.
7
Rogers, J. A. Nanomesh on-skin electronics. Nat. Nanotechnol. 2017, 12, 839–840.
8
Wang, C.; Hwang, D.; Yu, Z. B.; Takei, K.; Park, J.; Chen, T.; Ma, B. W.; Javey, A. User-interactive electronic skin for instantaneous pressure visualization. Nat. Mater. 2013, 12, 899–904.
9
Yokota, T.; Zalar, P.; Kaltenbrunner, M.; Jinno, H.; Matsuhisa, N.; Kitanosako, H.; Tachibana, Y.; Yukita, W.; Koizumi, M.; Someya, T. Ultraflexible organic photonic skin. Sci. Adv. 2016, 2, e1501856.
10
Kim, Y.; Chortos, A.; Xu, W. T.; Liu, Y. X.; Oh, J. Y.; Son, D.; Kang, J.; Foudeh, A. M.; Zhu, C. X.; Lee, Y. A bioinspired flexible organic artificial afferent nerve. Science 2018, 360, 998–1003.
11
Akbari, M. K.; Zhuiykov, S. A bioinspired optoelectronically engineered artificial neurorobotics device with sensorimotor functionalities. Nat. Commun. 2019, 10, 3873.
12
Zhang, X. M.; Zhuo, Y.; Luo, Q.; Wu, Z. H.; Midya, R.; Wang, Z. R.; Song, W. H.; Wang, R.; Upadhyay, N. K.; Fang, Y. L. et al. An artificial spiking afferent nerve based on mott memristors for neurorobotics. Nat. Commun. 2020, 11, 51.
13
Keene, S. T.; Lubrano, C.; Kazemzadeh, S.; Melianas, A.; Tuchman, Y.; Polino, G.; Scognamiglio, P.; Cinà, L.; Salleo, A.; Van De Burgt, Y. et al. A biohybrid synapse with neurotransmitter-mediated plasticity. Nat. Mater. 2020, 19, 969–973.
14
Sim, K.; Rao, Z. Y.; Zou, Z. N.; Ershad, F.; Lei, J. M.; Thukral, A.; Chen, J.; Huang, Q. A.; Xiao, J. L.; Yu, C. J. Metal oxide semiconductor nanomembrane–based soft unnoticeable multifunctional electronics for wearable human-machine interfaces. Sci. Adv. 2019, 5, eaav9653.
15
Wan, C. J.; Cai, P. Q.; Wang, M.; Qian, Y.; Huang, W.; Chen, X. D. Artificial sensory memory. Adv. Mater. 2020, 32, 1902434.
16
Wan, C. J.; Cai, P. Q.; Guo, X. T.; Wang, M.; Matsuhisa, N.; Yang, L.; Lv, Z. S.; Luo, Y. F.; Loh, X. J.; Chen, X. D. An artificial sensory neuron with visual-haptic fusion. Nat. Commun. 2020, 11, 4602.
17
Wan, H. C.; Cao, Y. Q.; Lo, L. W.; Zhao, J. Y.; Sepúlveda, N.; Wang, C. Flexible carbon nanotube synaptic transistor for neurological electronic skin applications. ACS Nano 2020, 14, 10402–10412.
18
Zang, Y. P.; Shen, H. G.; Huang, D. Z.; Di, C. A.; Zhu, D. B. A dual- organic-transistor-based tactile-perception system with signal-processing functionality. Adv. Mater. 2017, 29, 1606088.
19
Forrest, S. R. The path to ubiquitous and low-cost organic electronic appliances on plastic. Nature 2004, 428, 911–918.
20
Ruiz, C.; García-Frutos, E. M.; Hennrich, G.; Gómez-Lor, B. Organic semiconductors toward electronic devices: High mobility and easy processability. J. Phys. Chem. Lett. 2012, 3, 1428–1436.
21
Someya, T.; Bao, Z. N.; Malliaras, G. G. The rise of plastic bioelectronics. Nature 2016, 540, 379–385.
22
Lanzani, G. Organic electronics meets biology. Nat. Mater. 2014, 13, 775–776.
23
Sekitani, T.; Someya, T. Stretchable, large-area organic electronics. Adv. Mater. 2010, 22, 2228–2246.
24
Lipomi, D. J.; Bao, Z. N. Stretchable and ultraflexible organic electronics. MRS Bull. 2017, 42, 93–97.
25
Oh, J. Y.; Kim, S.; Baik, H. K.; Jeong, U. Conducting polymer dough for deformable electronics. Adv. Mater. 2016, 28, 4455–4461.
26
Kim, H. J.; Sim, K.; Thukral, A.; Yu, C. J. Rubbery electronics and sensors from intrinsically stretchable elastomeric composites of semiconductors and conductors. Sci. Adv. 2017, 3, e1701114.
27
Molina-Lopez, F.; Gao, T. Z.; Kraft, U.; Zhu, C.; Öhlund, T.; Pfattner, R.; Feig, V. R.; Kim, Y.; Wang, S.; Yun, Y. et al. Inkjet- printed stretchable and low voltage synaptic transistor array. Nat. Commun. 2019, 10, 2676.
28
Yang, Q.; Yang, H. H.; Lv, D. X.; Yu, R. J.; Li, E. L.; He, L. H.; Chen, Q. Z.; Chen, H. P.; Guo, T. L. High-performance organic synaptic transistors with an ultrathin active layer for neuromorphic computing. ACS Appl. Mater. Interfaces 2021, 13, 8672–8681.
29
Gao, W. T.; Zhu, L. Q.; Tao, J.; Wan, D. Y.; Xiao, H.; Yu, F. Dendrite integration mimicked on starch-based electrolyte-gated oxide dendrite transistors. ACS Appl. Mater. Interfaces 2018, 10, 40008–40013.
30
Yu, J. R.; Gao, G. Y.; Huang, J. R.; Yang, X. X.; Han, J.; Zhang, H.; Chen, Y. H.; Zhao, C. L.; Sun, Q. J.; Wang, Z. L. Contact-electrification- activated artificial afferents at femtojoule energy. Nat. Commun. 2021, 12, 1581.
31
Wei, H. H.; Shi, R. C.; Sun, L.; Yu, H. Y.; Gong, J. D.; Liu, C.; Xu, Z. P.; Ni, Y.; Xu, J. L.; Xu, W. T. Mimicking efferent nerves using a graphdiyne-based artificial synapse with multiple ion diffusion dynamics. Nat. Commun. 2021, 12, 1068.
32
Wang, X. M.; Yan, Y. J.; Li, E. L.; Liu, Y. Q.; Lai, D. X.; Lin, Z. X.; Liu, Y.; Chen, H. P.; Guo, T. L. Stretchable synaptic transistors with tunable synaptic behavior. Nano Energy 2020, 75, 104952.
33
Yu, F.; Zhu, L. Q.; Gao, W. T.; Fu, Y. M.; Xiao, H.; Tao, J.; Zhou, J. M. Chitosan-based polysaccharide-gated flexible indium tin oxide synaptic transistor with learning abilities. ACS Appl. Mater. Interfaces 2018, 10, 16881–16886.
34
Zhu, J. D.; Yang, Y. C.; Jia, R. D.; Liang, Z. X.; Zhu, W.; Rehman, Z. U.; Bao, L.; Zhang, X. X.; Cai, Y. M.; Song, L. et al. Ion gated synaptic transistors based on 2d van der Waals crystals with tunable diffusive dynamics. Adv. Mater. 2018, 30, 1800195.
35
Ohno, T.; Hasegawa, T.; Tsuruoka, T.; Terabe, K.; Gimzewski, J. K.; Aono, M. Short-term plasticity and long-term potentiation mimicked in single inorganic synapses. Nat. Mater. 2011, 10, 591–595.
36
Gu, J. H.; Park, M.; Kang, K.; Shin, H. C. Morse code representation using emg signals. In 2019 International Conference on Information and Communication Technology Convergence (ICTC), Jeju, Korea, 2019, pp 1059–1061.
Pages 758-764
Cite this article:
Shim H, Jang S, Jang JG, et al. Fully rubbery synaptic transistors made out of all-organic materials for elastic neurological electronic skin. Nano Research, 2022, 15(2): 758-764. https://doi.org/10.1007/s12274-021-3602-x
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