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Nano Research 2022, 15(1): 694-700 https://doi.org/10.1007/s12274-021-3549-y
Research Article | Issue | Published: 10 September 2021

Single-walled carbon nanotube based SERS substrate with single molecule sensitivity

Show Author's Information Chenmaya Xia,  Daqi Zhang,  Henan Li,  Sheng Li,  Haoming Liu,  Li Ding,  Xiyan Liu,  Min Lyu,  Ruoming Li,  Juan Yang( ),  Yan Li( )
Beijing National Laboratory for Molecular Sciences Key Laboratory for the Physics and Chemistry of Nanodevices State Key Laboratory of Rare Earth Materials Chemistry and Applications College of Chemistry and Molecular Engineering Peking UniversityBeijing 100871 China
Keywords:
gold, surface-enhanced Raman scattering, single-walled carbon nanotubes, single molecule studies
Topics:
Single walled carbon nanotubes (SWCN)
Cite this article:
Xia C, Zhang D, Li H, et al. Single-walled carbon nanotube based SERS substrate with single molecule sensitivity. Nano Research, 2022, 15(1): 694-700. https://doi.org/10.1007/s12274-021-3549-y
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Abstract Full text Electronic supplementary material About this article

In single molecule study, surface-enhanced Raman scattering (SERS) has the advantage of specifically providing structural information of the molecules targeted. The main challenge in single molecule SERS is developing reusable plasmonic substrates that ensures single molecule sensitivity and acquires intrinsic information of molecules. Here, we proposed a strategy to utilize single- walled carbon nanotubes (SWNTs) to construct SERS substrates. Employing ultrasonic spray pyrolysis, we prepared in situ polyhedral gold nanocrystals closely spaced and attached to nanotubes, ensuring valid hot spots formed along the tube-walls. With such SERS substrates, we proved the single molecule detection by the statistical analysis based on the natural abundance of isotopes. Since SWNTs provide non-chemical bonding adsorption sites, our SERS substrates are easily reusable and have a unique advantage of preserving the intrinsic property of the molecules detected. Using SWNTs to build SERS substrates may become a powerful general strategy in various static and dynamic studies of single molecules.


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About this article

Single-walled carbon nanotube based SERS substrate with single molecule sensitivity

Show Author's information Chenmaya Xia, Daqi Zhang, Henan Li, Sheng Li, Haoming Liu, Li Ding, Xiyan Liu, Min Lyu, Ruoming Li, Juan Yang( ), Yan Li( )
Beijing National Laboratory for Molecular Sciences Key Laboratory for the Physics and Chemistry of Nanodevices State Key Laboratory of Rare Earth Materials Chemistry and Applications College of Chemistry and Molecular Engineering Peking UniversityBeijing 100871 China

Abstract

In single molecule study, surface-enhanced Raman scattering (SERS) has the advantage of specifically providing structural information of the molecules targeted. The main challenge in single molecule SERS is developing reusable plasmonic substrates that ensures single molecule sensitivity and acquires intrinsic information of molecules. Here, we proposed a strategy to utilize single- walled carbon nanotubes (SWNTs) to construct SERS substrates. Employing ultrasonic spray pyrolysis, we prepared in situ polyhedral gold nanocrystals closely spaced and attached to nanotubes, ensuring valid hot spots formed along the tube-walls. With such SERS substrates, we proved the single molecule detection by the statistical analysis based on the natural abundance of isotopes. Since SWNTs provide non-chemical bonding adsorption sites, our SERS substrates are easily reusable and have a unique advantage of preserving the intrinsic property of the molecules detected. Using SWNTs to build SERS substrates may become a powerful general strategy in various static and dynamic studies of single molecules.

Keywords: gold, surface-enhanced Raman scattering, single-walled carbon nanotubes, single molecule studies

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Publication history
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Acknowledgements

Publication history

Received: 05 March 2021
Revised: 24 April 2021
Accepted: 27 April 2021
Published: 10 September 2021
Issue date: January 2022

Copyright

© Tsinghua University Press and Springer-Verlag GmbH Germany, part of Springer Nature 2021

Acknowledgements

Acknowledgements

This research is financially supported by the National key R&D Progrom of China (No. 2016YFA0201904), the National Natural Science Foundation of China (Nos. 21873008 and 21631002), Beijing National Laboratory for Molecular Sciences (No. BNLMS- CXTD-202001) and Shenzhen Basic Research Project (No. JCYJ20170817113121505).

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