Wireless phototherapeutic contact lenses and glasses with red light-emitting diodes

Young-Geun Park; Eunkyung Cha; Hyeon Seok An; Kyoung-Pil Lee; Myoung Hoon Song; Hong Kyun Kim; Jang-Ung Park

doi:10.1007/s12274-019-2595-1

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Research Article

Wireless phototherapeutic contact lenses and glasses with red light-emitting diodes

Young-Geun Park^{¹^,²^,^§}, Eunkyung Cha^{¹^,²^,^§}, Hyeon Seok An^{¹^,²}, Kyoung-Pil Lee^³, Myoung Hoon Song^⁴, Hong Kyun Kim^³(

), Jang-Ung Park^{¹^,²}(

)

1Nano Science Technology Institute, Department of Materials Science and Engineering, Yonsei University, Seoul 03722, Republic of Korea

2Center for Nanomedicine, Institute for Basic Science (IBS), Seoul 03722, Republic of Korea

3Department of Ophthalmology, School of Medicine, Kyungpook National University, Daegu, 41944, Republic of Korea

4School of Materials Science and Engineering, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Korea

^§ Young-Geun Park and Eunkyung Cha contributed equally to this work.

Show Author Information

Graphical Abstract

Abstract

Light-mediated therapeutics have attracted considerable attention as a method for the treatment of ophthalmologic diseases, such as age-related macular degeneration, because of their non-invasiveness and the effectiveness to ameliorate the oxidative stress of retinal cells. However, the current phototherapeutic devices are opaque, bulky, and tethered forms, so they are not feasible for use in continuous treatment during the patient’s daily life. Herein, we report wireless, wearable phototherapeutic devices with red light-emitting diodes for continuous treatments. Red light-emitting diodes were formed to be conformal to three-dimensional surfaces of glasses and contact lenses. Furthermore, fabricated light-emitting diodes had either transparency or a miniaturized size so that the user’s view is not obstructed. Also, these devices were operated wirelessly with control of the light intensity. In addition, in-vitro and in-vivo tests using human retinal epithelial cells and a live rabbit demonstrated the effectiveness and reliable operation as phototherapeutic devices.

Keywords

transparent electronics wearable healthcare red light-emitting diodes phototherapies

Electronic Supplementary Material

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Nano Research

Volume 13 Issue 5,
May 2020

Pages 1347-1353

DOI: 10.1007/s12274-019-2595-1

Cite this article:

Park Y-G, Cha E, Seok An H, et al. Wireless phototherapeutic contact lenses and glasses with red light-emitting diodes. Nano Research, 2020, 13(5): 1347-1353. https://doi.org/10.1007/s12274-019-2595-1

Topics:

Ophthalmology Patient treatment Wearable technology

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Received: 11 August 2019

Revised: 16 October 2019

Accepted: 06 November 2019

Published: 17 December 2019