AI Chat Paper
Note: Please note that the following content is generated by AMiner AI. SciOpen does not take any responsibility related to this content.
{{lang === 'zh_CN' ? '文章概述' : 'Summary'}}
{{lang === 'en_US' ? '中' : 'Eng'}}
Chat more with AI
Powered by AMiner. Clicking this button will take you away from SciOpen.
Home Nano Research Article
Article Link
Cite
EndNote(RIS) BibTeX
Collect
Submit Manuscript
Show Outline
Outline
Show full outline
Hide outline
Outline
Show full outline
Hide outline
Research Article

X-ray-induced radiophotodynamic therapy (RPDT) using lanthanide micelles: Beyond depth limitations

Slávka Kaščáková1,2, Alexandre Giuliani1,3, Sara Lacerda4, Agnès Pallier4, Pascal Mercère1, Éva Tóth4, Matthieu Réfrégiers1( )
Synchrotron SOLEILL'Orme des Merisiers91190Gif-sur-Yvette, France
UMR-S1193Université Paris-Sud XI94800Villejuif, France
INRACaractérisation et Élaboration des Produits Issus de l'Agriculture44316Nantes, France
Centre de Biophysique MoléculaireCNRSRue Charles Sadron45071Orléans Cedex 2, France
Show Author Information

Abstract

We report lanthanide-based micelles integrating hypericin (Hyp) for X-ray-triggered photodynamic therapy (PDT). The lanthanide luminescence induced by X-ray irradiation excites the photosensitizer, which leads to the generation of singlet oxygen. This versatile approach can be extended to other photosensitizers or other types of liponanoparticles and can allow for magnetic resonance imaging (MRI) guidance.

Graphical Abstract

Keywords

photodynamic therapyliponanoparticlesX-raydeep tumourphotosensitizer

Electronic Supplementary Material

Download File(s)
12274_2015_747_MOESM1_ESM.pdf (1.2 MB)

References

【1】
【1】
 
 
Crossref Google Scholar
Nano Research
Volume 8 Issue 7,
July 2015
Pages 2373-2379
DOI: 10.1007/s12274-015-0747-5

{{item.num}}

Comments on this article

Go to comment

< Back to all reports

Review Status: {{reviewData.commendedNum}} Commended , {{reviewData.revisionRequiredNum}} Revision Required , {{reviewData.notCommendedNum}} Not Commended Under Peer Review

Review Comment

Cite this Report
Close
Close
Cite this article:
Kaščáková S, Giuliani A, Lacerda S, et al. X-ray-induced radiophotodynamic therapy (RPDT) using lanthanide micelles: Beyond depth limitations. Nano Research, 2015, 8(7): 2373-2379. https://doi.org/10.1007/s12274-015-0747-5

1428

Views

80

Crossref

N/A

Web of Science

84

Scopus

4

CSCD
Received: 24 December 2014
Revised: 03 February 2015
Accepted: 10 February 2015
Published: 20 May 2015
© Tsinghua University Press and Springer-Verlag Berlin Heidelberg 2015