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Nano Research 2015, 8(3): 731-742 https://doi.org/10.1007/s12274-014-0556-2
Research Article | Issue | Published: 13 September 2014

Bimetallic nano-mushrooms with DNA-mediated interior nanogaps for high-efficiency SERS signal amplification

Show Author's Information Jianlei Shen1,  Jing Su1,  Juan Yan1,  Bin Zhao1,  Dongfang Wang1,  Siyi Wang2,  Kun Li1,  Mengmeng Liu1,  Yao He2,  Sanjay Mathur3,  Chunhai Fan1,  Shiping Song1,3( )
Division of Physical Biology & Bioimaging CenterShanghai Synchrotron Radiation FacilityShanghai Institute of Applied PhysicsChinese Academy of SciencesShanghai201800China
Institute of Functional Nano & Soft Materials (FUNSOM) and Jiangsu KeyLaboratory for Carbon-based Functional Materials & DevicesSoochow UniversitySuzhou215123China
Institute of Inorganic ChemistryUniversity of CologneCologneD-50939Germany
Keywords:
surface-enhanced Raman scattering, gold nanoparticle, biometallic nanostructure, nano-mushroom, nanogap
Cite this article:
Shen J, Su J, Yan J, et al. Bimetallic nano-mushrooms with DNA-mediated interior nanogaps for high-efficiency SERS signal amplification. Nano Research, 2015, 8(3): 731-742. https://doi.org/10.1007/s12274-014-0556-2
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Abstract Full text Electronic supplementary material About this article

Uniform silver-containing metal nanostructures with well-defined nanogaps hold great promise for ultrasensitive surface-enhanced Raman scattering (SERS) analyses. Nevertheless, the direct synthesis of such nanostructures with strong and stable SERS signals remains extremely challenging. Here, we report a DNA-mediated approach for the direct synthesis of gold-silver nano-mushrooms with interior nanogaps. The SERS intensities of these nano-mushrooms were critically dependent on the area of the nanogap between the gold head and the silver cap. We found that the formation of nanogaps was finely tunable by controlling the surface density of 6-carboxy-X-rhodamine (ROX) labeled single-stranded DNA (ssDNA) on the gold nanoparticles. We obtained nano-mushrooms in high yield with a high SERS signal enhancement factor of ~1.0 × 109, much higher than that for Au-Ag nanostructures without nanogaps. Measurements for single nanomushrooms show that these structures have both sensitive and reproducible SERS signals.


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Electronic supplementary material
About this article

Bimetallic nano-mushrooms with DNA-mediated interior nanogaps for high-efficiency SERS signal amplification

Show Author's information Jianlei Shen1, Jing Su1, Juan Yan1, Bin Zhao1, Dongfang Wang1, Siyi Wang2, Kun Li1, Mengmeng Liu1, Yao He2, Sanjay Mathur3, Chunhai Fan1, Shiping Song1,3( )
Division of Physical Biology & Bioimaging CenterShanghai Synchrotron Radiation FacilityShanghai Institute of Applied PhysicsChinese Academy of SciencesShanghai201800China
Institute of Functional Nano & Soft Materials (FUNSOM) and Jiangsu KeyLaboratory for Carbon-based Functional Materials & DevicesSoochow UniversitySuzhou215123China
Institute of Inorganic ChemistryUniversity of CologneCologneD-50939Germany

Abstract

Uniform silver-containing metal nanostructures with well-defined nanogaps hold great promise for ultrasensitive surface-enhanced Raman scattering (SERS) analyses. Nevertheless, the direct synthesis of such nanostructures with strong and stable SERS signals remains extremely challenging. Here, we report a DNA-mediated approach for the direct synthesis of gold-silver nano-mushrooms with interior nanogaps. The SERS intensities of these nano-mushrooms were critically dependent on the area of the nanogap between the gold head and the silver cap. We found that the formation of nanogaps was finely tunable by controlling the surface density of 6-carboxy-X-rhodamine (ROX) labeled single-stranded DNA (ssDNA) on the gold nanoparticles. We obtained nano-mushrooms in high yield with a high SERS signal enhancement factor of ~1.0 × 109, much higher than that for Au-Ag nanostructures without nanogaps. Measurements for single nanomushrooms show that these structures have both sensitive and reproducible SERS signals.

Keywords: surface-enhanced Raman scattering, gold nanoparticle, biometallic nanostructure, nano-mushroom, nanogap

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Publication history
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Acknowledgements

Publication history

Received: 06 June 2014
Revised: 28 July 2014
Accepted: 05 August 2014
Published: 13 September 2014
Issue date: March 2015

Copyright

© Tsinghua University Press and Springer‐Verlag Berlin Heidelberg 2014

Acknowledgements

Acknowledgements

We thank the National Basic Research Program of China (973 program) (Nos. 2013CB932802 and 2012CB932600), Alexander von Humboldt Foundation, and the National Natural Science Foundation of China (Nos. 91127037 and 91123037) for financial support.

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