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Research Article

Redox-sensitive colorimetric polyaniline nanoprobes synthesized by a solvent-shift process

Jihye Choi1,§, Yoochan Hong2,§, Eugene Lee3, Myeong-Hoon Kim1, Dae Sung Yoon2, Jinsuck Suh3,4,5, Yongmin Huh3,4,5, Seungjoo Haam1,4( ), Jaemoon Yang3,4,6( )
Department of Chemical and Biomolecular Engineering Yonsei UniversitySeoul 120-749 Republic of Korea
Department of Biomedical Engineering Yonsei UniversityWonju 220-710 Republic of Korea
Department of Radiology College of Medicine Yonsei UniversitySeoul 120-752 Republic of Korea
YUHS-KRIBB Medical Convergence Research InstituteSeoul 120-752 Republic of Korea
Severance Biomedical Science Institute (SBSI)Seoul 120-752 Republic of Korea
Severance Integrative Research Institute for Cerebral and Cardiovascular Diseases Yonsei University Health SystemSeoul 120-752 Republic of Korea

§These authors contributed equally to this work

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Abstract

We have synthesized water-stable polyaniline nanoparticles coated with tri-armed polyethylene glycol chains using a solvent-shift method and confirmed their colloidal size and aqueous solubility. Furthermore, we have demonstrated that the polyaniline nanoparticles can be doped with biological dopants to produce distinct color changes allowing the detection of live cancer cells.

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Keywords

polyanilinesolvent-shiftingcancercolorimetricnanoprobe

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Nano Research
Volume 6 Issue 5,
May 2013
Pages 356-364
DOI: 10.1007/s12274-013-0312-z

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Cite this article:
Choi J, Hong Y, Lee E, et al. Redox-sensitive colorimetric polyaniline nanoprobes synthesized by a solvent-shift process. Nano Research, 2013, 6(5): 356-364. https://doi.org/10.1007/s12274-013-0312-z

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Received: 27 December 2012
Revised: 26 February 2013
Accepted: 24 March 2013
Published: 13 April 2013
© Tsinghua University Press and Springer‐Verlag Berlin Heidelberg 2013