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Nano Research 2008, 1(6): 457-464 https://doi.org/10.1007/s12274-008-8048-x
Research Article | Open Access | Issue | Published: 01 December 2008

InAs/InP/ZnSe Core/Shell/Shell Quantum Dots as Near-Infrared Emitters: Bright, Narrow-Band, Non-Cadmium Containing, and Biocompatible

Show Author's Information Renguo Xie1,  Kai Chen2,  Xiaoyuan Chen2,  Xiaogang Peng1( )
Department of Chemistry and Biochemistry University of ArkansasFayettevilleAR 72701 USA
Molecular Imaging Program at Stanford (MIPS) Department of Radiology and Bio-X Program Stanford University School of MedicineStanfordCA 94305-5484 USA
Keywords:
Quantum dots, toxicity, InAs, near-infrared (NIR)
Cite this article:
Xie R, Chen K, Chen X, et al. InAs/InP/ZnSe Core/Shell/Shell Quantum Dots as Near-Infrared Emitters: Bright, Narrow-Band, Non-Cadmium Containing, and Biocompatible. Nano Research, 2008, 1(6): 457-464. https://doi.org/10.1007/s12274-008-8048-x
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Abstract Full text About this article

High quality InAs/InP/ZnSe core/shell/shell quantum dots have been grown by a one-pot approach. This engineered quantum dots with unique near-infrared (NIR) fluorescence, possessing outstanding optical properties, and the biocompatibility desired for in vivo applications. The resulting quantum dots have significantly lower intrinsic toxicity compared to NIR emissive dots containing elements such as cadmium, mercury, or lead. Also, these newly developed ultrasmall non-Cd containing and NIR-emitting quantum dots showed significantly improved circulation half-life and minimal reticuloendothelial system (RES) uptake.


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About this article

InAs/InP/ZnSe Core/Shell/Shell Quantum Dots as Near-Infrared Emitters: Bright, Narrow-Band, Non-Cadmium Containing, and Biocompatible

Show Author's information Renguo Xie1, Kai Chen2, Xiaoyuan Chen2, Xiaogang Peng1( )
Department of Chemistry and Biochemistry University of ArkansasFayettevilleAR 72701 USA
Molecular Imaging Program at Stanford (MIPS) Department of Radiology and Bio-X Program Stanford University School of MedicineStanfordCA 94305-5484 USA

Abstract

High quality InAs/InP/ZnSe core/shell/shell quantum dots have been grown by a one-pot approach. This engineered quantum dots with unique near-infrared (NIR) fluorescence, possessing outstanding optical properties, and the biocompatibility desired for in vivo applications. The resulting quantum dots have significantly lower intrinsic toxicity compared to NIR emissive dots containing elements such as cadmium, mercury, or lead. Also, these newly developed ultrasmall non-Cd containing and NIR-emitting quantum dots showed significantly improved circulation half-life and minimal reticuloendothelial system (RES) uptake.

Keywords: Quantum dots, toxicity, InAs, near-infrared (NIR)

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Publication history

Received: 16 October 2008
Revised: 26 October 2008
Accepted: 26 October 2008
Published: 01 December 2008
Issue date: December 2008

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© Tsinghua Press and Springer-Verlag 2008

Acknowledgements

Acknowledgements

This work was supported in part by the National Cancer Institute (NCI) (R21 CA121842, P50 CA114747, and U54 CA119367), the National Institute of Health (R43 EB005072), and the National Science Foundation (CHE-0554812).

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This article is published with open access at Springerlink.com

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