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Artificial intelligence (AI) is revolutionizing ophthalmology by providing innovative solutions for disease screening, diagnosis, personalized treatment, and the delivery of global healthcare services. This review explores the current state of AI research and applications in the field of ophthalmology, and the applications of telemedicine as well as clinical trials demonstrating AI's utility in reducing diagnostic time and improving treatment outcomes. It also analyzes the challenges faced in practical applications, including economic constraints, data privacy issues, and regulatory hurdles. The review highlights the future directions of AI integration, including highly accurate AI diagnosis, the formulation of personalized treatment plans, AI‐assisted surgical treatment, wearable medical devices, and telemedicine connectivity technologies. In addition, collaborative efforts among academia, the industry, and policymakers are crucial for overcoming these obstacles and fully unleashing the potential of AI in achieving equitable, efficient, and personalized ophthalmic healthcare services.

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