Osteoporotic vertebral fracture (OVF) is a common complication in patients with osteoporosis. The quality and functional status of the muscles around the spine are one of the important factors influencing the occurrence of OVF. Muscles play a role in both the mechanical and chemical interactions with adjacent bones. The muscles surrounding the spine influence the macrostructure and microstructure of spinal vertebrae through various mechanisms to protect and maintain the stability and strength of the spine. However, abnormal muscle quality and function can have a negative impact on the vertebrae. Screening for muscle quality and function in individuals at risk of OVF using radiographic, physical, and other biochemical methods can be employed for secondary prevention. Meanwhile, utilizing various increasingly mature novel nanomolecular technologies can have a positive impact on the treatment of OVF and vertebral strength, mitigating the clinical consequences of OVF onset.

Looking back on the development of radiomics in osteosarcoma over recent years, in addition to distinguishing osteosarcoma from other malignant bone tumors (mainly Ewing's sarcoma), more research directions are using radiomics to evaluate and predict the efficacy and survival of patients undergoing neoadjuvant chemotherapy. Among the three commonly used examination methods of X‐ray, CT, and magnetic resonance imaging (MRI), more and more studies have been conducted on MRI‐based radiomics, which fully reflects the advantages of MRI's high soft tissue contrast, multi‐sequence imaging, and most of the studies used a combination of imaging features and clinical features to make predictions. Some articles also considered relevant laboratory examination results and more and more studies are performing external verification. The field is now gradually developing toward multidimensional data and multicenter cooperation and data sharing.