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Volume 34 Issue 1, December 2026
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27 articles
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Review | Open Access
The Efficacy and Safety of B-Cell Maturation Antigen (BCMA) Antibody-Drug Conjugates (ADC) in Development against Cancer: A Systematic Review
Jing Shan, Catherine King, Harunor Rashid, Veysel Kayser
Published: 30 December 2025
2026, 34(1): 1
Review | Open Access
The Role of Exosomes as a Key Factor of Cytostatic Resistance in Cancer: Mechanisms of Action, Potential Biomarkers, and Possible Exosome-Based Therapies
Sandra Kałużna, Monika Świerczewska, Sylwia Ciesiółka, [...], Małgorzata Partyka, Michał Nowicki, Karolina Wojtowicz << Fewer
Published: 30 December 2025
2026, 34(1): 2
Review | Open Access
Effectiveness and Safety of Lenvatinib and Everolimus after Immune Checkpoint Inhibitors in Metastatic Renal Cell Cancer: A Systematic Review
Giacomo Iovane, Luca Traman, Michele Maffezzoli, [...], Giuseppe Fornarini, Domenico Corradi, Debora Guareschi, Matteo Santoni, Sebastiano Buti << Fewer
Published: 30 December 2025
2026, 34(1): 3
Review | Open Access
Circulating Tumor DNA in Cervical Cancer: Clinical Utility and Medico-Legal Perspectives
Abdulrahman K. Sinno, Aisha Mustapha, Navya Nair, [...], Simona Zaami, Lina De Paola, Valentina Billone, Eleonora Conti, Giuseppe Gullo, Pasquale Patrizio << Fewer
Published: 30 December 2025
2026, 34(1): 4
Review | Open Access
RP11-Derived Long Non-Coding RNAs in Hepatocellular Carcinoma: Hidden Treasures in Plain Sight
Se Ha Jang, Hyung Seok Kim, Jung Woo Eun
Published: 30 December 2025
2026, 34(1): 5
Review | Open Access
Male Breast Cancer: Epidemiology, Diagnosis, Molecular Mechanisms, Therapeutics, and Future Prospective
Ashok Kumar Sah, Ranjay Kumar Choudhary, Velilyaeva Alie Sabrievna, [...], Karomatov Inomdzhon Dzhuraevich, Anass M. Abbas, Manar G. Shalabi, Nadeem Ahmad Siddique, Raji Rubayyi Alshammari, Navjyot Trivedi, Rabab H. Elshaikh << Fewer
Published: 30 December 2025
2026, 34(1): 7
Review | Open Access
Ferroptosis: Mechanisms, Comparison with Cuproptosis and Emerging Horizons in Therapeutics
Shujie Yin, Zong Li, Wen-Bin Ou
Published: 30 December 2025
2026, 34(1): 8
Review | Open Access
Branched-Chain Amino Acid Metabolic Reprogramming and Cancer: Molecular Mechanisms, Immune Regulation, and Precision Targeting
Dongchi Cai, Jialin Ji, Chunhui Yang, Hong Cai
Published: 30 December 2025
2026, 34(1): 9
Article | Open Access
Real-World Outcomes of First-Line Palbociclib Plus Endocrine Therapy for HR+/HER2− Metastatic Breast Cancer in Japan: A Single-Center Retrospective Study
Keiko Yanagihara, Masato Yoshida, Kensaku Awaji, [...], Tamami Yamakawa, Sena Kato, Miki Tamura, Koji Nagata << Fewer
Published: 30 December 2025
2026, 34(1): 11
Article | Open Access
PNP as a Metabolic and Prognostic Driver of Breast Cancer Aggressiveness: Insights from Patient Tissue and Cell Models
Sarra B. Shakartalla, Iman M. Talaat, Nival Ali, [...], Shahenaz S. Salih, Zainab M. Al Shareef, Noura Alkhayyal, Riyad Bendardaf, Sameh S. M. Soliman << Fewer
Published: 30 December 2025
2026, 34(1): 13
Article | Open Access
P2RX1 Influences the Prognosis of Ph+/Ph-Like ALL through Energy and Calcium Metabolism
Xiangmei Ye, Baoyi Yang, Xin Zhang, [...], Luyuan Yang, Likun Zhang, Qin Ren, Xiaobing Li, Leiguang Feng, Lanlan Wei, Peng Song, Yuqing Ye, Xin Lian, Yujuan Gao, Haidi Tang, Zhiyu Liu << Fewer
Published: 30 December 2025
2026, 34(1): 14
Article | Open Access
ZMIZ2/MCM3 Axis Participates in Triple-Negative Breast Cancer Progression
Xiaopan Zou, Meiyang Sun, Xin Jiang, [...], Jingze Yu, Xiaomeng Li, Bingyu Nie << Fewer
Published: 30 December 2025
2026, 34(1): 15
Article | Open Access
CBX4 Drives Gastric Cancer Progression by Activating β-Catenin Signaling
Wendong Jia, Ting Zhang, Ziying Zhang, [...], Lingzhi Wu, Xihao Fu, Zhenxin Wang, Ni Yin << Fewer
Published: 30 December 2025
2026, 34(1): 16
Article | Open Access
CSRNP1 Promotes Apoptosis and Mitochondrial Dysfunction via ROS-Mediated JNK/p38 MAPK Pathway Activation in Hepatocellular Carcinoma
Huihui Shi, Lei Chen, Juan Huang, [...], Xuejing Lin, Lei Huang, Min Tang, Kai Lu, Wenchao Wang, Maoling Zhu << Fewer
Published: 30 December 2025
2026, 34(1): 17
Article | Open Access
HE4 Might Participate in Extracellular Matrix Remodeling in Ovarian Cancer via Activation of Fibroblasts
Yimin Liu, Bin Liu, Huabin Gao, [...], Jinlong Wang, Jingya Duan, Xiaolan Huang, Yuexi Liu, Ying Huang, Wenjing Liao, Ruonan Li, Hua Linghu << Fewer
Published: 30 December 2025
2026, 34(1): 18
Article | Open Access
Pan-Cancer Analysis of Enhancer-Induced PAN3-AS1 and Experimental Validation as a WFDC13-Promoting Factor in Colon Cancer
Xu Guo, Yanan Yu, Xiaolin Ma, Yuanjie Cai
Published: 30 December 2025
2026, 34(1): 19
Article | Open Access
Application Value and Research Frontiers of Immunotherapy in Glioblastoma: A Bibliometric and Visualized Analysis
Kun Deng, Jianliang Huang, Danyang Li, [...], Wei Gao, Minghua Wu, Mingsheng Lei << Fewer
Published: 30 December 2025
2026, 34(1): 20
Article | Open Access
ELK4 Promotes Vasculogenic Mimicry in Oral Squamous Cell Carcinoma via Driving DHFR Transcriptional Activation
Yongle Qiu, Kunshan Li, Wenjing Wang, [...], Wenjuan Zhang, Jilun Liu, Yang Bai, Fei Xu, Jie Guo << Fewer
Published: 30 December 2025
2026, 34(1): 21
Article | Open Access
Integrative Multi-Omics Analysis and Experiments Validation Identify COX5B as a Novel Therapeutic Target for Lung Adenocarcinoma
Lv Ling, Minying Lu, Ling Ye, [...], Yuanhang Chen, Sheng Lin, Jun Yang, Yu Rong, Guixiong Wu << Fewer
Published: 30 December 2025
2026, 34(1): 22
Article | Open Access
Development of Patient-Derived Conditionally Reprogrammed 3D Breast Cancer Culture Models for Drug Sensitivity Evaluation
Jing Cai, Haoyun Zhu, Weiling Guo, [...], Ting Huang, Pangzhou Chen, Wen Zhou, Ziyun Guan << Fewer
Published: 30 December 2025
2026, 34(1): 23
Article | Open Access
STC2+ Malignant Cell State Associated with EMT, Tumor Microenvironment Remodeling, and Poor Prognosis Revealed by Single-Cell and Spatial Transcriptomics in Colorectal Cancer
Kai Gui, Tianyi Yang, Chengying Xiong, [...], Yue Wang, Zhiqiang He, Wuxian Li, Min Tang << Fewer
Published: 30 December 2025
2026, 34(1): 24
Article | Open Access
ETV4-Mediated PD-L1 Upregulation Promotes Immune Evasion and Predicts Poor Immunotherapy Response in Melanoma
Tao Zhu, Taofeng Wei, Mingdong Yang, [...], Junjun Xu, Huifang Jiang, Wei He, Juyan Zheng, Haibin Dai << Fewer
Published: 30 December 2025
2026, 34(1): 25
Article | Open Access
miR-512-3p/RPS6KA2 Axis Regulates Cisplatin Resistance in Ovarian Cancer via Autophagy and Ferroptosis
Jianfa Wu, Huang Chen, Sihong Wang, [...], Lei Peng, Xiaoying Hu, Zhou Liu << Fewer
Published: 30 December 2025
2026, 34(1): 26
Article | Open Access
AGPAT3 Regulates Immune Microenvironment in Osteosarcoma via Lysophosphatidic Acid Metabolism
Shenghui Su, Yu Zeng, Jiaxin Chen, Xieping Dong
Published: 30 December 2025
2026, 34(1): 27
Retraction | Open Access
Retraction: Truncated Bid Overexpression Induced by Recombinant Adenovirus Cre/LoxP System Suppresses the Tumorigenic Potential of CD133+ Ovarian Cancer Stem Cells
Published: 30 December 2025
2026, 34(1): 28
Retraction | Open Access
Retraction: MicroRNA-133b Inhibits Proliferation, Cellular Migration, and Invasion via Targeting LASP1 in Hepatocarcinoma Cells
Published: 30 December 2025
2026, 34(1): 29
Retraction | Open Access
Retraction: MicroRNA-148a Acts as a Tumor Suppressor in Osteosarcoma via Targeting Rho-Associated Coiled-Coil Kinase
Published: 30 December 2025
2026, 34(1): 30