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Article | Open Access

An In Vitro Investigation of 5-Aminolevulinic Acid Mediated Photodynamic Therapy in Bone Sarcoma

Rebecca H. Maggs, Marcus J. Brookes, Kenneth S. Rankin

Published: 19 January 2026

2026, 34(2): 1

Review | Open Access

Evolution or Revolution in Colorectal Cancer Treatment: Present and Future of New Therapeutic Options. A Narrative Review

Urszula Częścik, Martyna Gryglas, Arkadiusz Szterk, Sylwia Flis

Published: 19 January 2026

2026, 34(2): 2

Review | Open Access

Unveiling the Anticancer Potential of Urolithin A in Colorectal Cancer: A Systematic Review

Mariana Francisco, Fernando Mendes, Diana Martins, Joana Liberal

Published: 19 January 2026

2026, 34(2): 3

Review | Open Access

The Frontier of Melanoma Treatment: Defeating Immunotherapy Resistance—A Systematic Review

Kamila Mozga, Olga Synowiecka, Igor Rydzyk, [...], Anna Marek, Ewelina Wieczorek, Alicja Petniak, Paulina Gil-Kulik << Fewer

Published: 19 January 2026

2026, 34(2): 4

Review | Open Access

A Holistic Review of Oncological Drug Targets and Trajectories of Resistance in Cancer Therapy

Harpreet Kaur, Dhrubalochan Rana, Sowvik Bag, Paramjeet Singh

Published: 19 January 2026

2026, 34(2): 5

Review | Open Access

Targeting Sphingolipids in Breast Cancer: From Tumor Biology to Therapeutic Strategies

Min Hee Kim, Boyoon Huh, Joo-Won Park, Woo-Jae Park

Published: 19 January 2026

2026, 34(2): 6

Review | Open Access

Clinical Molecular Pathology and Treatment Developments in Advanced Uveal Melanoma: State of the Art

Stefano Dore, Matteo Sacchi, Antonio Pinna, [...], Giuseppe Palmieri, Panagiotis Paliogiannis << Fewer

Published: 19 January 2026

2026, 34(2): 7

Review | Open Access

Parasitic Infections and Carcinogenesis: Molecular Mechanisms, Immune Modulation, and Emerging Therapeutic Strategies

Marta Pawłowska, Dorian Jarek, Jan Milanowski, Karolina Szewczyk-Golec

Published: 19 January 2026

2026, 34(2): 8

Review | Open Access

Progression on Mechanism and Therapeutic Implications of Neddylation in Lung Cancer

Jiayu Zou, Yajie Lu, Jiaqi Li, [...], Zhaokai Zhou, Fu Peng, Pu Qiu, Hailin Tang, Cheng Peng << Fewer

Published: 19 January 2026

2026, 34(2): 9

Review | Open Access

Cancer-Associated Fibroblasts in Prostate Cancer: Unraveling Mechanisms and Therapeutic Implications

Yang Wu, Dong Xu, Run Shi, [...], Mingwei Zhan, Shaohui Xu, Xin Wang, Jianpeng Zhang, Zhaokai Zhou, Weizhuo Wang, Yongjie Wang, Minglun Li, Zihao Xu, Kaifeng Su << Fewer

Published: 19 January 2026

2026, 34(2): 10

Article | Open Access

Prognostic Value of Circulating Tumor Cells and Cancer Associated Macrophage-Like Cells in Metastatic Non-Small Cell Lung Cancer Patients: A Retrospective Exploratory Analysis

Marco Siringo, Michela De Meo, Alain Jonathan Gelibter, [...], Chiara Nicolazzo, Paola Gazzaniga << Fewer

Published: 19 January 2026

2026, 34(2): 11

Article | Open Access

Detection of KRAS, NRAS and BRAF Mutations in Liquid Biopsy from Patients with Colorectal Cancer

Katerina Ondraskova, Matous Cwik, Ondrej Horky, [...], Jitka Berkovcova, Jitka Holcakova, Martin Bartosik, Tomas Kazda, Klara Mrazova, Michal Uher, Igor Kiss, Roman Hrstka << Fewer

Published: 19 January 2026

2026, 34(2): 12

Article | Open Access

Serum Extracellular Vesicle-Associated GULP1 Is a Key Indicator of Hepatocellular Carcinoma

Hyung Seok Kim, Ju A Son, Minji Kang, [...], Soon Sun Kim, Geum Ok Baek, Moon Gyeong Yoon, Se Ha Jang, Dokyung Jung, Ji Eun Han, Jae Youn Cheong, Jung Woo Eun << Fewer

Published: 19 January 2026

2026, 34(2): 13

Article | Open Access

BHLHE40 Is a Transcriptional Regulatory Target of NFE2L3 in Triple-Negative Breast Cancer

Shail Rakesh Modi, Terrick Andey, George Acquaah-Mensah

Published: 19 January 2026

2026, 34(2): 14

Article | Open Access

Utilization of a UPLC-MS/MS Approach to Elucidate the Role of ABCB1-Mediated Paclitaxel Resistance in Non-Small Cell Lung Cancer Cells

Sha Hu, Wenjing Wang, Qianfang Hu, [...], Rujuan Zheng, Qinghe Huang, Hui Shi, Xinyuan Ding, Wenjuan Wang, Zengyan Zhu << Fewer

Published: 19 January 2026

2026, 34(2): 16

Article | Open Access

PIK3R1 as a Gastric Cancer Biomarker Linked to CD73⁺ Treg-Mediated Immunosuppression

Bu Zou, Yi-En Xu, Hui-Chan He, [...], Zu-Lu Ye, Da-Lei Zhou, Cai-Yun He, Chan Huang << Fewer

Published: 19 January 2026

2026, 34(2): 17

Article | Open Access

Development and Assessment of a Novel Palmitoylation-Related lncRNA Signature for Prognosis and Immune Landscape in Hepatocellular Carcinoma

Zhilong He, Jing Qin, Sixuan Wu, [...], Xian Liang, Yu Liu, Jinfeng Qiu, Zhimin Li, Kai Hu << Fewer

Published: 19 January 2026

2026, 34(2): 18

Article | Open Access

A Retrospective Real-World Study: The Efficacy and Safety of Immune Checkpoint Inhibitors Combined with Chemoradiotherapy in Limited-Stage Small Cell Lung Cancer

Ruoxue Cai, Shuyi Hu, Feiyang Li, [...], Huanhuan Sha, Guoren Zhou, Ying Fang << Fewer

Published: 19 January 2026

2026, 34(2): 19

Article | Open Access

Thimerosal Inhibits Tumor Malignant Progression through Direct Action and Enhancing the Efficacy of PD-1-Based Immunotherapy

Ping Wang, Yan-Han Chen, Ze-Tao Zhan, [...], Jun-Xiang Zeng, Yu Chen, Yuan Lin, Tao Chen, Wei-Jie Zhou << Fewer

Published: 19 January 2026

2026, 34(2): 20

Article | Open Access

The FN1-ITGB4 Axis Drives Acquired Chemoresistance in Bladder Cancer by Activating FAK Signaling

Xiaoyu Zhang, RenFei Zong, Yan Sun, [...], Nan Chen, Kunyao Zhu, Hang Tong, Tinghao Li, Junlong Zhu, Zijia Qin, Linfeng Wu, Aimin Wang, Weiyang He << Fewer

Published: 19 January 2026

2026, 34(2): 21

Article | Open Access

Esketamine Enhances the Chemosensitivity of Colorectal Adenocarcinoma Cells to 5-Fluorouracil via AMPK/mTOR/HMMR Signaling Pathway

Yuerou Feng, Panpan Tong, Shuwen Fu, [...], Xiaofan Lu, Liquan Zheng, Jielan Lai, Renchun Lai << Fewer

Published: 19 January 2026

2026, 34(2): 22

Article | Open Access

Gut Associated Metabolites Enhance PD-L1 Blockade Efficacy in Prostate Cancer

Ke Liu, Xia Xue, Haiming Qin, [...], Jiaying Zhu, Meng Jin, Die Dai, Youcai Tang, Ihtisham Bukhari, Hangfan Liu, Chunjing Qiu, Feifei Ren, Pengyuan Zheng, Yang Mi, Weihua Chen << Fewer

Published: 19 January 2026

2026, 34(2): 23

Article | Open Access

RNF145 Promotes Hepatocellular Carcinoma Metastasis through Ubiquitination and Degradation of PCDH9

Huan Zhang, Zhangwendi Xu, Yien Xu, [...], Mao Li, Lingrui Liu, Caiyun He, Wenhuan Zhong, Jiliang Qiu << Fewer

Published: 19 January 2026

2026, 34(2): 24

Article | Open Access

SDHA Deficiency in Hepatocellular Carcinoma Promotes Tumor Progression through Succinate-Induced M2 Macrophage Polarization

Xinyang Li, Luyuan Ma, Chuan Shen, [...], Ruolan Gu, Shilong Dong, Mingjie Liu, Ying Xiao, Wenpeng Liu, Yuexia Liu, Caiyan Zhao << Fewer

Published: 19 January 2026

2026, 34(2): 25