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Home Oncology Research All Issues Volume 34 Issue 4
Volume 34 Issue 4, March 2026
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Article | Open Access
Serum Biomarkers in Bladder Cancer: NMR Metabolomics for Identification and Monitoring during Platinum-Based Therapy
Roberta Giorgione, Daniela Grasso, Elisabetta Gambale, [...], Federico Scolari, Virginia Rossi, Fabrizio Di Maida, Marinella Micol Mela, Barbara Marzocchi, Laura Doni, Adriano Pasqui, Andrea Minervini, Enrico Caliman, Sergio Serni, Andrea Bernini, Serena Pillozzi, Lorenzo Antonuzzo << Fewer
Published: 23 March 2026
2026, 34(4)
Review | Open Access
Novel Immunotherapeutic Approaches for Patients with Head and Neck Cutaneous Squamous Cell Carcinoma
Adam Khorasanchi, Merve Hasanov, Richard Wu, [...], Hisham Alsharif, Kari Kendra, Claire Verschraegen << Fewer
Published: 23 March 2026
2026, 34(4)
Review | Open Access
Roles of ADP-Ribosyltransferases in Cancer
Maureen Veilleux, Anh Nguyen, Charles Cao, Yihui Shi
Published: 23 March 2026
2026, 34(4)
Review | Open Access
Epigenetics of Malignant Melanoma: Mechanisms, Diagnostic Approaches and Therapeutic Applications
Sophiette G. Hong, George F. Murphy, Christine G. Lian
Published: 23 March 2026
2026, 34(4)
Review | Open Access
Ferroptosis as a Translational Axis in Small Cell Lung Cancer: A Systematic Review of Redox Pathways and Precision Oncology Prospects
Donatella Coradduzza, Anna La Salvia, Giuseppe Fanciulli, Maria Rosaria De Miglio
Published: 23 March 2026
2026, 34(4)
Review | Open Access
Understanding the Tumor Microenvironmental Mechanisms Driving Immunotherapy Resistance in Colorectal Cancer Liver Metastases
Candela Cives-Losada, Cristiana Soldani, Michela Anna Polidoro, [...], Barbara Franceschini, Ana Lleo, Marcello Di Martino, Matteo Donadon << Fewer
Published: 23 March 2026
2026, 34(4)
Review | Open Access
Recent Advances in Radiopharmaceuticals for Cancer Diagnosis and Therapy
Ye Ri Han, Sang Bong Lee
Published: 23 March 2026
2026, 34(4)
Review | Open Access
Surgery Alone Treatment vs. Surgery with Adjuvant Therapy for Laryngeal Mucoepidermoid Cancer: A Systematic Review
Francesco Chiari, Giovanni Motta, Daria Maria Filippini, [...], Claudio Donadio Caporale, Pierre Guarino << Fewer
Published: 23 March 2026
2026, 34(4)
Review | Open Access
Next-Generation Hydrogel Platforms for Effective Localized Cancer Therapy: Advances in Biologics, Immunotherapeutics, and Gene Delivery
Vincenzo Montanarella, Marcelo Guerrero, David Filho, [...], Júlia German-Cortés, Giacomoluciano Vitelli, Magalí Sureda, Carlos Pavón Regaña, Roser Ferrer, Simó Schwartz, Esteban Durán-Lara, Fernanda Andrade, Diana Rafael << Fewer
Published: 23 March 2026
2026, 34(4)
Review | Open Access
Emerging Chimeric Antigen Receptor-Immune Cell Therapy for Pancreatic Cancer: Mechanisms, Clinical Advances, and Future Perspectives
Shuo Wang, Miao Wang, Wei Yao
Published: 23 March 2026
2026, 34(4)
Review | Open Access
Advances in Metabolic Reprogramming and Immune Regulatory Mechanisms in Lung Cancer
Xiaomeng Li, Xuejiao Li, Hongbo Wu, Rui Li
Published: 23 March 2026
2026, 34(4)
Review | Open Access
Disulfidptosis: A Metabolic Cell Death Mechanism with Therapeutic Potential in Cancer
Wubin Zhao, Qi Wang, Jun Zhang
Published: 23 March 2026
2026, 34(4)
Review | Open Access
Efficacy and Mechanisms of CDK4/6 Inhibitors in Breast Cancer: Advancing Targeted Therapeutic Strategies
Mohsina Patwekar, Faheem Patwekar, Zulhisyam Abdul Kari, [...], Muhammad Rajaei Ahmad Mohd Zain, Arifullah Mohammed, Rohit Sharma << Fewer
Published: 23 March 2026
2026, 34(4)
Article | Open Access
Discovery of Two Novel Pyrazole Derivatives as Anticancer Agents Targeting Tubulin Polymerization and MAPK Signaling Pathways
Denisse A. Gutierrez, Elisa Robles-Escajeda, Jose A. Lopez-Saenz, [...], Robert A. Kirken, Edgar A. Borrego, Ana P. Betancourt, Soumya Nair, Sourav Roy, Armando Varela-Ramirez, Renato J. Aguilera << Fewer
Published: 23 March 2026
2026, 34(4)
Article | Open Access
Cytokines IL-6, IL-10, and CCL5 Secreted by Infiltrating B Cells Promote Cell Migration of Human Prostate Cancer Cell Lines
Crystal J. Byrd, Monasia Evans, Woojung Kim, [...], Quintera Knight, Geou-Yarh Liou << Fewer
Published: 23 March 2026
2026, 34(4)
Article | Open Access
The Effect of Metformin on Atezolizumab/Bevacizumab Treatment in Patients with Hepatocellular Carcinoma and Diabetes
Andrea Dalbeni, Marco Vicardi, Leonardo A. Natola, [...], Alessandra Auriemma, Bernardo Stefanini, Caterina Vivaldi, Piera Federico, Andrea Polloni, Caterina Soldà, Lorenzo Lani, Ingrid Garajová, Stefano Tamberi, Stefania De Lorenzo, Fabio Piscaglia, Vincenzo Di Maria, Gianluca Masi, Sara Lonardi, Giovanni Brandi, Bruno Daniele, Franco Trevisani, Gianluca Svegliati-Baroni, Laura Schiada, Fabio Marra, Claudia Campani, Ciro Celsa, Giuseppe Cabibbo, Mariangela Bruccoleri, Massimo Iavarone, Leonardo Stella, Francesca R. Ponziani, Tiziana Pressiani, Lorenza Rimassa, Francesco Tovoli, David Sacerdoti << Fewer
Published: 23 March 2026
2026, 34(4)
Article | Open Access
Inhibitory Effect of Progesterone on Breast Cancer Progression and Migration via the Regulation of Epithelial-Mesenchymal Transition
So-Ye Jeon, Zeeshan Ahmad Bhutta, Hong Kyu Lee, Kyung-Chul Choi
Published: 23 March 2026
2026, 34(4)
Article | Open Access
Oxidative Stress Footprints in Bone Marrow Mesenchymal Stem Cells from Untreated Advanced Breast Cancer
Francisco Raúl Borzone, María Belén Giorello, Agustina Freire, [...], Leandro Marcelo Martinez, Leonardo Feldman, Federico Dimase, Pablo Evelson, Irene Larripa, Emilio Batagelj, Marcela Beatriz González Cid, Norma Alejandra Chasseing << Fewer
Published: 23 March 2026
2026, 34(4)
Article | Open Access
Eco-Friendly Combat against Prostate Cancer: Green Chemistry Approach Using Biosynthesized Nanoparticles Functionalized with Propolis for Enhanced Anticancer Activity
Awatif Rashed Z. Almotairy, Eman Fayad, Fatimah Hadadi, [...], Ahmad F. Alhomodi, Dalal Nasser Binjawhar, Hanadi A. Katouah, Bassma H. Elwakil, Keshav Raj Paudel, Mostafa El-Khatib << Fewer
Published: 23 March 2026
2026, 34(4)
Article | Open Access
Sunitinib and Fenofibrate as Combination Therapy for MDR Glioblastoma: Insights from In Vitro and In Silico Studies
Saad Alobid, Hussam Albassam, Tebyan O. Mirgany, [...], Faris Almutairi, Mohammed Mufadhe Alanazi, Ahmed H. Bakheit, Hanadi H. Asiri, Eram Eltahir, Gamaleldin I. Harisa << Fewer
Published: 23 March 2026
2026, 34(4)
Article | Open Access
Multi-Scale Transcriptomic Sequencing Data Analysis Reveals LINC00467 is Associated with Malignant Progression in Breast Cancer: An In Silico and In Vitro Study
Hui Zha, Chao Li, Jia Chen, [...], Hao Bo, Zhaolan Hu, Zailong Qin, Jie Guo, Junbin Yuan << Fewer
Published: 23 March 2026
2026, 34(4)
Article | Open Access
Single-Cell and Multi-Omics-Based Characterization of Gastric Cancer Identifies TPP1 as a Potential Target for Gastric Cancer Progression and Treatment
Yingying Zhao, Jiakang Ma, Rujin Huang, Shuxian Pan
Published: 23 March 2026
2026, 34(4)
Article | Open Access
Lactic Acid Drives ESM1 to Attenuate DNA Damage and CD8+ T Cell Infiltration in Cancer
Yingzheng Tan, Jiao Xiao, Liyun Tang, [...], Jian Wan, Tian Zeng, Wenchao Zhou, Xueru Liu, Xun Chen, Yukun Li << Fewer
Published: 23 March 2026
2026, 34(4)
Article | Open Access
Comprehensive Bioinformatics Analysis and Experimental Verification RNF186 Is a Recurrence Signature Gene of Hepatocellular Carcinoma that Promotes Cell Proliferation
Shanbao Ke, Junya Yan, Xiao Feng, Baiyu Li
Published: 23 March 2026
2026, 34(4)
Article | Open Access
PSMD2-Mediated MAPK Signaling Promotes Bladder Cancer Development and Immune Microenvironment Remodeling
Shuwen Sun, Jingcheng Zhang, Zongtai Zheng, [...], Yajuan Hao, Tianyuan Xu, Ji Liu, Liang Sun, Aimin Wang, Yadong Guo, Shiyu Mao, Xu Zhang, Yunfei Xu, Yifan Chen, Yang Yan << Fewer
Published: 23 March 2026
2026, 34(4)
Article | Open Access
ONX-0914 Suppresses Hormone-Sensitive Prostate Cancer by Promoting O-GlcNAcylation-Mediated Stabilization of TCF7L1
Peng Xian, Zhenwei Feng, Haitao Yu, [...], Hubin Yin, Haonan Chen, Tenglin Shi, Xilai Li, Chunlin Zhang, Xuesong Bai, Xin Gou, Xinyuan Li, Jie Li << Fewer
Published: 23 March 2026
2026, 34(4)
Article | Open Access
OTUD4 Inhibits Prostate Cancer by Deubiquitinating MYH9
Zheng Qin, Yueyao Zhang, Dongze Liu, [...], Xiaokang Zheng, Kaibin Wang, Xiao Zhu, Yuanhao Zhang, Kexin Xu, Changying Li, Lijuan Kang, Lili Wang, Haitao Wang << Fewer
Published: 23 March 2026
2026, 34(4)
Article | Open Access
Nanoliposome-Encapsulated Semiconductor Particles and Arsenic Trioxide Synergistically Enhance Chemo-Photothermal Therapy for Lung Cancer
Chang He, An Wang, Youbo Wang, [...], Qinyun Ma, Xiaofeng Chen << Fewer
Published: 23 March 2026
2026, 34(4)
Article | Open Access
piR-37524 Overexpression in Colorectal Cancer: A Potential Diagnostic Bio-Marker and Therapeutic Target
Jiaxi Li, Deepak Iyer, Siming Sui, [...], Zheng Huang, Ryan Wai-Yan Sin, Abraham Tak-Ka Man, Wai-Lun Law, Chi-Chung Foo, Lui Ng << Fewer
Published: 23 March 2026
2026, 34(4)
Article | Open Access
KNL1 Regulates Ferroptosis Resistance and Migration in Lung Adenocarcinoma Cells via AMPK-mTOR Signaling
Yiran Dong, Jingyue Wang, Jiayang Chen, [...], Liang Mo, Yong You << Fewer
Published: 23 March 2026
2026, 34(4)
Case Report | Open Access
Adolescent Renal Tumours: Diagnostic and Therapeutic Challenges in a Transitional Age Group—A Multidisciplinary Case Report Series from a Single Center
Antonio Ruggiero, Fernando Fuccillo, Valerio Di Paola, [...], Alberto Romano, Palma Maurizi, Dario Talloa, Nazario Foschi, Pierluigi Russo, Marco Racioppi, Stefano Mastrangelo, Giorgio Attinà << Fewer
Published: 23 March 2026
2026, 34(4)
Viewpoint | Open Access
Lorlatinib and Amivantamab: A Paradigm Shift in EGFR and ALK Positive NSCLC, with More Effective but More Toxic Treatments Requiring a Well-Structured Shared Decision Making
Paolo Maione, Valentina Palma, Cesare Gridelli
Published: 23 March 2026
2026, 34(4)
Case Report | Open Access
BRAFV600E Metastatic Synovial Sarcoma Treated with BRAF & MEK Inhibitors Achieves Complete Response. A Case Report & Literature Review
Daniel Burg, Aryeh Babkoff, Omer Or, [...], Noam Olshinka, Jonathan Abraham Demma, Mohamad Adila, Marc Wygoda, Philip Blumenfeld, Judith Diment, Masha Galiner, Yusef Azraq, Daniela Katz, Petachia Reissman, Sadie Ostrowicki, Gabriella Sebbag, Narmine Elkhateeb, Anat Hershko Moshe, Dania Jaber, Adi Hollander, Limor Rubin, Aviad Zick << Fewer
Published: 23 March 2026
2026, 34(4)
Retraction | Open Access
Retraction: TRAF4 Regulates Migration, Invasion, and Epithelial–Mesenchymal Transition via PI3K/AKT Signaling in Hepatocellular Carcinoma
Published: 23 March 2026
2026, 34(4)
Retraction | Open Access
Retraction: MicroRNA-520b Functions as a Tumor Suppressor in Colorectal Cancer by Inhibiting Defective in Cullin Neddylation 1 Domain Containing 1 (DCUN1D1)
Published: 23 March 2026
2026, 34(4)
Retraction | Open Access
Retraction: MicroRNA 125a-5p Inhibits Cell Proliferation and Induces Apoptosis in Hepatitis B Virus-Related Hepatocellular Carcinoma by Downregulation of ErbB3
Published: 23 March 2026
2026, 34(4)