Cancer Biology & Medicine Open Access Editor-in-Chief: Xishan Hao
Home Cancer Biology & Medicine All Issues Volume 22 Issue 12
Volume 22 Issue 12, December 2025
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PP. 1423-1647
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14 articles
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EDITORIAL
Editorial | Open Access
Harnessing the STING pathway for HCC treatment
Carmen Chak-Lui Wong, Cerise Yuen-Ki Chan, Helen Do-Gai Xue, Chun-Ming Wong
Published: 15 December 2025
2025, 22(12): 1423-1430
PERSPECTIVE
Perspective | Open Access
From bone marrow to the tumor microenvironment: how neutrophil maturation shapes cancer immunity
Tao Shi, Yiran Cai, Hanbing Wang, Jia Wei
Published: 15 December 2025
2025, 22(12): 1431-1438
REVIEW
Review | Open Access
Current status of traditional Chinese medicine in modulating mitochondrial metabolic abnormalities in tumors
Siyi Ma, Jiarong Li, Bingjie Hao, Lihong Fan
Published: 23 September 2025
2025, 22(12): 1439-1454
Review | Open Access
Primary cilia in cancer: structures, functions, mechanisms, and therapeutic implications
Miaomiao Zheng, Jun Zhou, Yijie Wang
Published: 24 November 2025
2025, 22(12): 1455-1472
Review | Open Access
Harnessing the power of cancer-associated fibroblasts to revolutionize pancreatic cancer treatment
Jian Shen, Ruopu Wu, Tao Yin, [...], Qun Wang, Lei Nie << Fewer
Published: 04 December 2025
2025, 22(12): 1473-1492
Review | Open Access
From residual risk to precision intervention: the evolving role of minimal residual disease in breast cancer management
Junnan Xu, Kun Fang, Xiaoxi Li, [...], Li Han, Shulan Sun, Tao Sun << Fewer
Published: 28 November 2025
2025, 22(12): 1493-1514
Review
Review | Open Access
Current status of management of immune-related adverse events and practical needs for oncologist education
Binhe Tian, Yuanmei Yang, Shuman Kuang, [...], Mingjian Piao, Chengjie Li, Haitao Zhao, Hanping Wang << Fewer
Published: 23 September 2025
2025, 22(12): 1515-1536
LETTER
Letter | Open Access
COX-2 inhibition synergizes with radioimmunotherapy by promoting TCF1+CD8+ T cell infiltration in NSCLC
Lin Ma, Menglin Bai, Yao Wang, [...], Xueying Zhai, Jinming Yu, Xiangjiao Meng << Fewer
Published: 22 October 2025
2025, 22(12): 1537-1543
Letter | Open Access
Immunotherapy rechallenge of patients with advanced NSCLC progression after sequential treatment with third-generation EGFR-TKI and immunotherapy
Shuyi Hu, Zipeng Wu, Yingying Dai, [...], Xinhong Shi, Qin Hu, Caolu Liu, Yifei Zhu, Ruofan Yu, Jingwen Li, Ying Liu, Tianyi Liu, Lin Lu, Chengyun Yao, Bo Shen, Meiqi Shi, Cheng Chen, Xiaohua Wang, Guoren Zhou << Fewer
Published: 10 December 2025
2025, 22(12): 1544-1552
Letter | Open Access
Effectiveness of postoperative adjuvant radiochemotherapy versus radiotherapy in thoracic esophageal squamous cell carcinoma with lymph node metastasis: a multicenter randomized study
Jiangfeng Wang, Wenhui Shen, Xiaojiang Sun, [...], Ding Wang, Youhua Jiang, Weimin Mao << Fewer
Published: 01 December 2025
2025, 22(12): 1553-1557
Original Article
Original Article | Open Access
CLT-003 exerts anti-tumor activity in pancreatic cancer by blocking the PI3K/AKT/HIF-1α pathway
Chao Xu, Zekun Li, Yueying Shan, [...], Chunhua She, Yanfang Yang, Tianxing Zhou, Yongjie Xie, Bo Ni, Chenyang Meng, Guangcong Shen, Boyang Fu, Guannan Sheng, Liangliang Wu, Jinlong Pei, Tiansuo Zhao, Song Gao, Hongwei Wang, Chengqi Deng, Kaiyuan Wang, Antao Chang, Chongbiao Huang, Lei Shi, Shengyu Yang, Jun Yu, Jihui Hao, Xiuchao Wang << Fewer
Published: 30 September 2025
2025, 22(12): 1558-1577
ORIGINAL ARTICLE
Original Article | Open Access
Chidamide suppresses macrophage-mediated immune evasion and tumor progression in small cell lung cancer by targeting the STAT4/CCL2 signaling pathway
Wenting Liu, Ting Mei, Yantao Jiang, [...], Jingya Wang, Mengjie Li, Liuchun Wang, Zhaoting Meng, Tingting Qin, Dingzhi Huang << Fewer
Published: 23 October 2025
2025, 22(12): 1578-1604
Original Article | Open Access
Comprehensive investigation of the molecular basis of cancer dependencies suggests therapeutic options for breast cancer
Rui Ding, Zhiming Shao, Tianjian Yu
Published: 23 October 2025
2025, 22(12): 1605-1626
Original Article | Open Access
Nintedanib enhances tumor cell radiosensitivity by promoting ferroptosis and modulating the ATF4/SLC7A11/GSH axis
Chunya Li, Aifeina Aili, Qingqing Yu, [...], Mu Yang, Qiyuan Feng, Duo Xu, Bo Liu, Jingyao Tu, Xianglin Yuan << Fewer
Published: 19 November 2025
2025, 22(12): 1627-1647