Genes & Diseases Open Access Editors-in-Chief: Ailong Huang, Tong-Chuan He
Home Genes & Diseases All Issues Volume 12 Issue 1
Volume 12 Issue 1, January 2025
LETTERS
Letter | Open Access
Mutational and transcriptional profiling of cuproptosis-associated genes in amyotrophic lateral sclerosis
Published: 14 January 2024
2025, 12(1): 101208
Letter | Open Access
Low CXCR6 expression drives extracellular matrix remodeling and enhances cell proliferation in OSCC
Published: 17 January 2024
2025, 12(1): 101213
Letter | Open Access
Single-cell transcriptomics illustrates the immune inflammatory responses of septic mice spleen after capsaicin treatment
Published: 05 March 2024
2025, 12(1): 101256
Letter | Open Access
The link between ten-eleven translocation-2 (Tet2) related clonal hematopoiesis and sequential onset of two hematologic malignancies
Published: 22 March 2024
2025, 12(1): 101270
Letter | Open Access
TFR2 gene alterations in idiopathic erythrocytosis reinforce a possible relation between erythrocytosis and iron metabolism
Published: 05 April 2024
2025, 12(1): 101291
Letter | Open Access
Epidermal second-hit mutation in MVK gene associated with linear porokeratosis
Published: 29 April 2024
2025, 12(1): 101314
RAPID COMMUNICATIONS
Rapid Communication | Open Access
PPAN modulates mouse male germ cell development via maintaining nucleolar homeostasis
Published: 03 January 2024
2025, 12(1): 101204
Rapid Communication | Open Access
In situ transcriptomic analysis of spermatocytes in non-obstructive azoospermia reveals senescence-like states in arrested spermatocytes
Published: 03 January 2024
2025, 12(1): 101205
Rapid Communication | Open Access
Integrative network analysis identifies pivotal host genes and pathways for SARS-CoV-2 infection
Published: 03 January 2024
2025, 12(1): 101206
Rapid Communication | Open Access
CARM1 accelerates the growth of liver cancer cells by enhancing ARAF
Published: 23 August 2024
2025, 12(1): 101395
Rapid Communication | Open Access
Single-cell sequencing reveals the immune microenvironment associated with gastric cancer
Published: 26 January 2024
2025, 12(1): 101218
Rapid Communication | Open Access
Single-cell sequencing revealed the microglia-activated cell distribution in gray matter heterotopia
Published: 01 February 2024
2025, 12(1): 101235
Rapid Communication | Open Access
Analysis of mutations in Chinese patients with polycystic kidney disease by targeted exome sequencing
Published: 28 February 2024
2025, 12(1): 101246
Rapid Communication | Open Access
The 21-base pair deletion mutant Calpain3 does not inhibit wild-type Calpain3 activity
Published: 08 April 2024
2025, 12(1): 101301
Rapid Communication | Open Access
Profiling the cell diversity and tissue structure of aqueous humor circulatory system in human eyes using spatial single-cell RNA sequencing
Published: 12 April 2024
2025, 12(1): 101304
Rapid Communication | Open Access
Fact or fiction — Exploring resident mesenchymal stem cells in abdominal aortic aneurysm from multiple perspectives
Published: 14 January 2024
2025, 12(1): 101210
Rapid Communication | Open Access
CircDONSON regulates the proliferation, invasion and migration of non-small cell lung cancer cells through the MAPK signaling pathway
Published: 23 January 2024
2025, 12(1): 101217
Rapid Communication | Open Access
CDK9 inhibitor elicits APC through a synthetic lethal effect in colorectal cancer cells
Published: 24 January 2024
2025, 12(1): 101220
Rapid Communication | Open Access
Exploring biomarkers of MAPK pathway co-expression in lung adenocarcinoma and their functions based on machine learning algorithms and single-cell analysis
Published: 26 January 2024
2025, 12(1): 101222
Rapid Communication | Open Access
Mutations in GTPBP3 cause aberrant mitochondrial respiration associated with combined oxidative phosphorylation deficiency 23
Published: 02 February 2024
2025, 12(1): 101232
Rapid Communication | Open Access
Chimeric RNA landscape in the placenta: A transcriptomic analysis revealing novel diagnostic biomarkers forpreeclampsia
Published: 09 February 2024
2025, 12(1): 101242
Rapid Communication | Open Access
Novel virulence-related genes that contribute to clinical infections of Salmonella enteritidis
Published: 01 February 2024
2025, 12(1): 101236
Rapid Communication | Open Access
EGCG alleviates vascular calcification via the MAPK/JunB signaling pathway
Published: 01 February 2024
2025, 12(1): 101237
Rapid Communication | Open Access
Functional impact of the head domain variants of DES (Desmin) on filament assembly
Published: 02 February 2024
2025, 12(1): 101238
Rapid Communication | Open Access
Establishment of a mouse model of respiratory mycoplasma challenged intranasally combined intraperitoneally eliciting chronic inflammation and lung consolidation
Published: 09 February 2024
2025, 12(1): 101243
Rapid Communication | Open Access
Genetic feature diversity of KRAS-mutated colorectal cancer and the negative association of DNA mismatch repair deficiency relevant mutational signatures with prognosis
Published: 26 February 2024
2025, 12(1): 101245
Rapid Communication | Open Access
Lengthening of the CHURC1 3’ untranslated region by alternative polyadenylation is associated with the progression of acute myeloid leukemia
Published: 28 February 2024
2025, 12(1): 101248
Rapid Communication | Open Access
CircAkap7: A novel circular RNA with a role in Doxorubicin-induced cardiotoxicity
Published: 02 March 2024
2025, 12(1): 101253
Rapid Communication | Open Access
Heterogeneity of anoikis in triple-negative breast cancer subtyping and therapeutic implications
Published: 04 March 2024
2025, 12(1): 101255
Rapid Communication | Open Access
Disulfidptosis heterogeneity in breast cancer uncovers PTTG1IP as an actionable therapeutic target
Published: 05 March 2024
2025, 12(1): 101257
Rapid Communication | Open Access
Heterozygous deletion of Cul4b in female mice leads to ovulatory dysfunction and female infertility
Published: 24 July 2024
2025, 12(1): 101381
Rapid Communication | Open Access
Time-series transcriptome analysis mapping pulmonary immune checkpoint atlas of experimental silicosis
Published: 08 March 2024
2025, 12(1): 101258
Rapid Communication | Open Access
Identification of ferroptosis/autophagy-related genes and potential underlying mechanisms involved in the effect of BMSC senescence on the osteogenic differentiation of aging BMSCs
Published: 08 March 2024
2025, 12(1): 101259
Rapid Communication | Open Access
EBF1 expressed in the dermal papilla regulates hair type and length
Published: 07 March 2024
2025, 12(1): 101261
Rapid Communication | Open Access
The combination of SLC7A11 inhibitor and oridonin synergistically inhibits cervical cancer cell growth by decreasing the NADPH/NADP+ ratio
Published: 19 March 2024
2025, 12(1): 101265
Rapid Communication | Open Access
NUF2 overexpression predicts poor outcomes in multiple myeloma
Published: 19 March 2024
2025, 12(1): 101268
Rapid Communication | Open Access
Identification of AAV serotypes for gene therapy in Krabbe iPSCs-derived brain organoids
Published: 19 March 2024
2025, 12(1): 101269
Rapid Communication | Open Access
Prevalence of synonymous mutations in m6A modification sites in human cancers
Published: 06 July 2024
2025, 12(1): 101373
Rapid Communication | Open Access
Novel heterozygous missense variants in the TOE1 gene linked to pontocerebellar hypoplasia type 7
Published: 08 April 2024
2025, 12(1): 101290
Rapid Communication | Open Access
Integrating single-cell RNA sequencing and bulk RNA sequencing data to predict acute respiratory distress syndrome in sepsis patients
Published: 19 March 2024
2025, 12(1): 101271
REVIEW ARTICLES
Review Article | Open Access
Known and unknown: Exosome secretion in tumor microenvironment needs more exploration
Published: 23 November 2023
2025, 12(1): 101175
Review Article | Open Access
Cap-specific terminal N6-methyladeonsine methylation of RNA mediated by PCIF1 and possible therapeutic implications
Published: 23 November 2023
2025, 12(1): 101181
Review Article | Open Access
Recent advances in methylation modifications of microRNA
Published: 23 December 2023
2025, 12(1): 101201
Review Article | Open Access
Guarding against digestive-system cancers: Unveiling the role of Chk2 as a potential therapeutic target
Published: 07 December 2023
2025, 12(1): 101191
Review Article | Open Access
Extrachromosomal circular DNA and their roles in cancer progression
Published: 22 December 2023
2025, 12(1): 101202
Review Article | Open Access
Research progress and the prospect of using single-cell sequencing technology to explore the characteristics of the tumor microenvironment
Published: 03 February 2024
2025, 12(1): 101239
Review Article | Open Access
Epigenetic regulation and its therapeutic potential in hepatitis B virus covalently closed circular DNA
Published: 03 February 2024
2025, 12(1): 101215
Review Article | Open Access
Development of novel osteoarthritis therapy by targeting AMPK-β-catenin-Runx2 signaling
Published: 24 February 2024
2025, 12(1): 101247
Review Article | Open Access
Regulation of SLC7A11 as an unconventional checkpoint in tumorigenesis through ferroptosis
Published: 02 March 2024
2025, 12(1): 101254
FULL LENGTH ARTICLES
Full Length Article | Open Access
Naked cuticle homolog 2 controls the differentiation of osteoblasts and osteoclasts and ameliorates bone loss in ovariectomized mice
Published: 12 January 2024
2025, 12(1): 101209
Full Length Article | Open Access
IGF2BP1 promotes multiple myeloma with chromosome 1q gain via increasing CDC5L expression in an m6A-dependent manner
Published: 17 January 2024
2025, 12(1): 101214
Full Length Article | Open Access
Progranulin deficiency associates with postmenopausal osteoporosis via increasing ubiquitination of estrogen receptor α
Published: 28 January 2024
2025, 12(1): 101221
Full Length Article | Open Access
TNFα-reliant FSP1 up-regulation promotes intervertebral disc degeneration via caspase 3-dependent apoptosis
Published: 28 February 2024
2025, 12(1): 101251
Full Length Article | Open Access
MAFB-mediated CEBPA regulated human urothelium growth through Wnt/β-catenin signaling pathway
Published: 13 September 2024
2025, 12(1): 101432