Genes & Diseases Open Access Editors-in-Chief: Ailong Huang, Tong-Chuan He
Home Genes & Diseases All Issues Volume 11 Issue 4
Volume 11 Issue 4, July 2024
LETTERS
Letter | Open Access
Systematic pan-cancer analysis reveals OGT and OGA as potential biomarkers for tumor microenvironment and therapeutic responses
Published: 09 September 2023
2024, 11(4): 101089
Letter | Open Access
Comprehensive characterization of cell disulfidptosis in human cancers: An integrated pan-cancer analysis
Published: 14 September 2023
2024, 11(4): 101095
Letter | Open Access
SARS-CoV-2 triggers Dickkopf-1 (Dkk-1) modulation of T helper cells and lung pathology in mice
Published: 15 November 2023
2024, 11(4): 101167
RAPID COMMUNICATIONS
Rapid Communication | Open Access
A novel preimplantation genetic testing strategy for a subtelomeric genetic disorder: A case study
Published: 04 July 2023
2024, 11(4): 101014
Rapid Communication | Open Access
Transcriptomic analysis reveals that NIBAN1 overexpression is associated with BRAFV600E mutation and increases the aggressiveness of thyroid cancer
Published: 14 September 2023
2024, 11(4): 101094
Rapid Communication | Open Access
Let-7i-5p maintains the stemness via R-spondin2/Wnt pathway in hepatocellular carcinoma
Published: 14 September 2023
2024, 11(4): 101096
Rapid Communication | Open Access
Intracellular zinc signaling via Krüppel-like transcription factor 6 promotes HuD expression in pancreatic β cell
Published: 16 October 2023
2024, 11(4): 101144
Rapid Communication | Open Access
Syrosingopine, an anti-hypertensive drug and lactate transporter (MCT1/4) inhibitor, activates hepatic stellate cells and exacerbates liver fibrosis in a mouse model
Published: 18 November 2023
2024, 11(4): 101169
Rapid Communication | Open Access
miR-933 accelerates the growth of liver cancer cells by enhancing pyruvate kinase isoform M2
Published: 30 November 2023
2024, 11(4): 101186
Rapid Communication | Open Access
Whole exome sequencing and functional validation identify CAPN1 variants as a cause of Chinese moyamoya disease
Published: 11 September 2023
2024, 11(4): 101090
Rapid Communication | Open Access
Implications of T cell-mediated tumor killing genes for molecular heterogeneity and clinical stratification in lung adenocarcinoma
Published: 08 November 2023
2024, 11(4): 101162
Rapid Communication | Open Access
Exploring the molecular landscape of NNK-induced transformation: A comprehensive genome-wide CRISPR/Cas9 screening
Published: 29 September 2023
2024, 11(4): 101131
Rapid Communication | Open Access
Aquaporin-3 promotes proliferation and inflammation in hepatocellular carcinoma
Published: 16 July 2023
2024, 11(4): 101029
Rapid Communication | Open Access
DLX3 (Q178R) mutation delays osteogenic differentiation via H19/miR-29c-3p/KDM5B axis in TDO-iPSCs-derived MSCs
Published: 03 July 2023
2024, 11(4): 101012
Rapid Communication | Open Access
LncRNA HOTTIP facilitated tumor growth via stimulating the hnRNPA2B1/DKK1/Wnt/β-catenin regulatory axis in hepatocellular carcinoma
Published: 04 July 2023
2024, 11(4): 101013
Rapid Communication | Open Access
Long non-coding RNA BANCR promotes pancreatic cancer lymphangiogenesis and lymphatic metastasis by regulating the HIF-1α/VEGF-C/VEGFR-3 pathway via miR-143-5p
Published: 04 July 2023
2024, 11(4): 101015
Rapid Communication | Open Access
Characterization of SH3GLB1 in the auditory system and its potential role in mitophagy
Published: 06 July 2023
2024, 11(4): 101018
Rapid Communication | Open Access
Chemotherapy-induced small extracellular vesicles prime the pre-metastatic niche to accelerate neuroblastoma metastasis
Published: 04 July 2023
2024, 11(4): 101017
Rapid Communication | Open Access
LncRNA HCP5-encoded protein contributes to adriamycin resistance through ERK/mTOR pathway-mediated autophagy in breast cancer cells
Published: 10 July 2023
2024, 11(4): 101024
Rapid Communication | Open Access
AI-driven analysis establishes the single base substitution signatures as personalized prognostic predictors for five-year survival of gastric cancer
Published: 13 July 2023
2024, 11(4): 101030
Rapid Communication | Open Access
Comprehensive genomic analysis of early and late-onset hepatocellular carcinoma
Published: 12 July 2023
2024, 11(4): 101031
Rapid Communication | Open Access
Single-cell transcriptomics systematically discloses the immune-inflammatory responses of peripheral blood mononuclear cells for diabetic nephropathy
Published: 13 July 2023
2024, 11(4): 101033
Rapid Communication | Open Access
SUV39H1-driven NFATc1 methylation is essential for the c-Cbl-mediated degradation of NFATc1 in an osteoclast lineage
Published: 14 July 2023
2024, 11(4): 101034
Rapid Communication | Open Access
Identification of TMEM217 as a novel prognostic biomarker and potential therapeutic target in acute myeloid leukemia
Published: 16 July 2023
2024, 11(4): 101037
Rapid Communication | Open Access
Prevention and treatment of gerbil hepatitis E using the programmable CRISPR-Cas13d system
Published: 24 July 2023
2024, 11(4): 101051
Rapid Communication | Open Access
Hsa_circ_0007099 and PIP4K2A coexpressed in diffuse large B-cell lymphoma with clinical significance
Published: 31 July 2023
2024, 11(4): 101056
Rapid Communication | Open Access
Deletion of heterogeneous nuclear ribonucleoprotein K in satellite cells leads to inhibited skeletal muscle regeneration in mice
Published: 17 August 2023
2024, 11(4): 101062
Rapid Communication | Open Access
Common interacting genetic variation shapes susceptibility to type 1 diabetes in a Colombian Caribbean community: In search of shared genetic markers
Published: 02 August 2023
2024, 11(4): 101058
Rapid Communication | Open Access
A prognostic model of patients with pancreatic cancer based on four N6-methyladenosine-related lncRNAs and analysis of related immune infiltration
Published: 13 October 2023
2024, 11(4): 101141
Rapid Communication | Open Access
Effects of COVID-19 pandemic on human fertility: A scientometric and visualized evaluation
Published: 27 September 2023
2024, 11(4): 101127
Rapid Communication | Open Access
Genotyping on circulating tumor DNA improves mutation detection rate in high-risk diffuse large B-cell lymphoma
Published: 20 September 2023
2024, 11(4): 101116
Rapid Communication | Open Access
C. elegans model of riboflavin transporter deficiency (RTD) disorder reveals deficits in synaptic transmission and movement
Published: 08 August 2023
2024, 11(4): 101071
Rapid Communication | Open Access
Resident to exhausted CD4+ T cell ratio is associated with the prognosis of gastric cancer
Published: 07 September 2023
2024, 11(4): 101076
Rapid Communication | Open Access
A novel heterozygous SF1/NR5A1 gene variant causes 46,XY DSD-gonadal dysgenesis with hypergonadotropic hypogonadism without adrenal insufficiency
Published: 04 November 2023
2024, 11(4): 101160
Rapid Communication | Open Access
M2 macrophage-related molecular subtypes and prognostic index for prostate cancer patients through integrating single-cell and bulk RNA sequencing analysis
Published: 09 September 2023
2024, 11(4): 101086
Rapid Communication | Open Access
Neutralization of SARS-CoV-2 infection by antibodies targeting diverse epitopes
Published: 09 September 2023
2024, 11(4): 101088
Rapid Communication | Open Access
Immunoglobulin superfamily containing leucine-rich repeat (ISLR) negatively regulates osteogenic differentiation through the BMP-Smad signaling pathway
Published: 09 September 2023
2024, 11(4): 101091
Rapid Communication | Open Access
Epinephrine promotes tumor progression and M2 polarization of tumor-associated macrophages by regulating the TRIM2- NF-κB pathway in colorectal cancer cells
Published: 14 September 2023
2024, 11(4): 101092
Rapid Communication | Open Access
Complement C1q induces the M2-polarization of tumor-associated macrophages in lung adenocarcinoma
Published: 13 September 2023
2024, 11(4): 101093
Rapid Communication | Open Access
Deletion of Axin1 in aggrecan-expressing cells leads to growth plate cartilage defects in adult mice
Published: 19 October 2023
2024, 11(4): 101147
Rapid Communication | Open Access
Incidental and secondary findings in trio exome sequencing
Published: 11 October 2023
2024, 11(4): 101137
REVIEW ARTICLES
Review Article | Open Access
The role of proteasomes in tumorigenesis
Published: 06 August 2023
2024, 11(4): 101070
Review Article | Open Access
Diverse functions of SOX9 in liver development and homeostasis and hepatobiliary diseases
Published: 24 June 2023
2024, 11(4): 100996
Review Article | Open Access
The key mediator of diabetic kidney disease: Potassium channel dysfunction
Published: 22 September 2023
2024, 11(4): 101119
Review Article | Open Access
Advances in single-cell sequencing technology in microbiome research
Published: 28 September 2023
2024, 11(4): 101129
Review Article | Open Access
The role of lipid metabolism in osteoporosis: Clinical implication and cellular mechanism
Published: 20 September 2023
2024, 11(4): 101122
Review Article | Open Access
Twenty years of Gendicine® rAd-p53 cancer gene therapy: The first-in-class human cancer gene therapy in the era of personalized oncology
Published: 31 October 2023
2024, 11(4): 101155
Review Article | Open Access
CRISPR, CAR-T, and NK: Current applications and future perspectives
Published: 19 September 2023
2024, 11(4): 101121
Review Article | Open Access
The roles and mechanisms of SREBP1 in cancer development and drug response
Published: 22 June 2023
2024, 11(4): 100987
Review Article | Open Access
Insights into the role of RNA m6A modification in the metabolic process and related diseases
Published: 04 July 2023
2024, 11(4): 101011
Review Article | Open Access
Advances in the application of hydrogel-based scaffolds for tendon repair
Published: 07 July 2023
2024, 11(4): 101019
FULL LENGTH ARTICLES
Full Length Article | Open Access
Single-cell transcriptomic analysis reveals transcript enrichment in oxidative phosphorylation, fluid sheer stress, and inflammatory pathways in obesity-related glomerulopathy
Published: 14 September 2023
2024, 11(4): 101101
Full Length Article | Open Access
Intranasal boosting with RBD-HR protein vaccine elicits robust mucosal and systemic immune responses
Published: 03 August 2023
2024, 11(4): 101066
Full Length Article | Open Access
PCK1 attenuates tumor stemness via activating the Hippo signaling pathway in hepatocellular carcinoma
Published: 16 September 2023
2024, 11(4): 101114
Full Length Article | Open Access
PDK1 promotes breast cancer progression by enhancing the stability and transcriptional activity of HIF-1α
Published: 15 July 2023
2024, 11(4): 101041
Full Length Article | Open Access
DNA-delivered monoclonal antibodies targeting the p53 R175H mutant epitope inhibit tumor development in mice
Published: 23 June 2023
2024, 11(4): 100994
Full Length Article | Open Access
CYP3A5 unexpectedly regulates glucose metabolism through the AKT–TXNIP–GLUT1 axis in pancreatic cancer
Published: 07 September 2023
2024, 11(4): 101079
Full Length Article | Open Access
A genomic association study revealing subphenotypes of childhood steroid-sensitive nephrotic syndrome in a larger genomic sequencing cohort
Published: 27 September 2023
2024, 11(4): 101126
Full Length Article | Open Access
Remodeling the immune microenvironment for gastric cancer therapy through antagonism of prostaglandin E2 receptor 4
Published: 10 November 2023
2024, 11(4): 101164
CORRIGENDA
Corrigendum | Open Access
Corrigendum to ‘Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics’ [Genes & Diseases 10 (2023) 1367–1401]
Published: 20 January 2024
2024, 11(4): 101211
Corrigendum | Open Access
Corrigendum to “SEMA4D acts as a novel oligogenic pathogenic gene of idiopathic hypogonadotropic hypogonadism through the PlexinB1/MET/RND1/RHOA/RAF1/MAPK signaling axis” [Genes & Diseases 10 (2023) 65–68]
Published: 22 March 2024
2024, 11(4): 101273