Genes & Diseases Open Access Editors-in-Chief: Ailong Huang, Tong-Chuan He
Home Genes & Diseases All Issues Volume 11 Issue 6
Volume 11 Issue 6, November 2024
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RAPID COMMUNICATIONS
Rapid Communication | Open Access
ZIP4 inhibits Ephrin-B1 ubiquitination, activating Wnt5A/JNK/ZEB1 to promote liver cancer metastasis
Haijun Guo, Renyi Su, Xinfeng Lu, [...], Hui Zhang, Xuyong Wei, Xiao Xu << Fewer
Published: 24 April 2024
2024, 11(6): 101312
Rapid Communication | Open Access
Targeting TMEM16A/ANO1 inhibits the progression of BRAF mutant (V600E) melanoma through the MEK/ERK and AKT signaling pathways
Meiyun Shi, Jiahui Wang, Xingyu Huang, [...], Linsu Liu, Lutao Liu, Na Zhou, Xinqi Shan, Huaqun Chen << Fewer
Published: 27 October 2023
2024, 11(6): 101153
Rapid Communication | Open Access
Spontaneous NETosis and type Ⅰ IFN signaling activation in resting neutrophils of chronic granulomatous disease patients with CYBB mutations
Zhengjing Lu, Wenjun Mou, Jianxin He, [...], Xuedong Ge, Xiaolin Wang, Jingang Gui << Fewer
Published: 20 September 2023
2024, 11(6): 101118
Rapid Communication | Open Access
Identification of a novel germline APC N-terminal pathogenic variant associated with attenuated familial adenomatous polyposis
Giovanna Forte, Valentina Grossi, Filomena Cariola, [...], Antonia Lucia Buonadonna, Paola Sanese, Katia De Marco, Candida Fasano, Martina Lepore Signorile, Vittoria Disciglio, Cristiano Simone << Fewer
Published: 07 September 2023
2024, 11(6): 101078
Rapid Communication | Open Access
Roles of Setbp1 in developmental hematopoiesis and acute myeloid leukemia
Fei Ao, Fan Chen, Minhong Lv, [...], Yuming Cao, Jinfeng Xu, Jingbo Xu, Anskar Yu-Hung Leung, Qiwen Yuan, Li Wang, Bailiang He << Fewer
Published: 13 December 2023
2024, 11(6): 101195
Rapid Communication | Open Access
RNA binding motif protein 43 (RBM43) suppresses hepatocellular carcinoma metastasis by regulating Slug mRNA stability
Yao Liu, Huan Feng, Qi Zhao, [...], Xiao Liang, Ying Wang, Shuai Xiao, Suqin Shen, Jiaxue Wu << Fewer
Published: 14 December 2023
2024, 11(6): 101192
Rapid Communication | Open Access
PDLIM1 sustains DNA damage response by promoting chromatin relaxation and activating DNA–PK complex
Yue Lang, Dexuan Gao, Lan Yu, [...], Xiang-Xiang Zhang, Debabrata Saha, Benjamin P.C. Chen, Meng-Meng Gu, Zeng-Fu Shang << Fewer
Published: 13 October 2023
2024, 11(6): 101139
Rapid Communication | Open Access
In-depth profiling of tumor tissue derived from malignant pleural mesothelioma patients identifies potential biomarkers predicting response to immune-checkpoint inhibitor therapy
Dmitrii Shek, Bo Gao, Hema Mahajan, [...], Adnan Nagrial, Matteo S. Carlino, Fabio Luciani, Scott A. Read, Golo Ahlenstiel << Fewer
Published: 03 December 2023
2024, 11(6): 101189
Rapid Communication | Open Access
Single-cell analyses revealed key tumor-infiltrating myeloid cell subsets associated with clinical outcomes in different subtypes of breast cancer
Dingjie Wu, Si Chen, Yijin Liu, [...], Bowen Yang, Ruixin Li, Feng Jin, Fan Yao, Yue Fang << Fewer
Published: 30 November 2023
2024, 11(6): 101185
Rapid Communication | Open Access
The efficacy and safety of NeuroWell antidepressant dietary supplement, Deanxit, and their combination in the treatment of mild-to-moderate depression: A randomized clinical trial
Honglei Yin, Zhuxin Sui, Yutong Wang, [...], Dechen Liu, Qinglu Wang, Yanchao Wang, Lei Sun, Jinfeng Li, Zhen Li, Yue Liu, Shang Guo, Wenwen Wang, Hongtao Yin, Ping Liu, Kezhong Zhang, Huaibo Zhang, Yajun Liu, Yanqiu Liu, Qiqi Zhou, Dianfang Wei, Hui Zhang, Shanshan Wang, Yaochao Ning, Shuang Geng, Xuejun Wen, Youping Deng, Hongwei Wang, Yunliang Wang << Fewer
Published: 13 December 2023
2024, 11(6): 101171
Rapid Communication | Open Access
Adeno-associated virus-mediated intraprostatic suppression of MIR375 inhibits tumor progression in the TRAMP mouse model of prostate cancer
Xianyanling Yi, Jin Li, Zeyu Han, [...], Tianyi Zhang, Dazhou Liao, Jia You, Jianzhong Ai << Fewer
Published: 23 November 2023
2024, 11(6): 101182
Rapid Communication | Open Access
Properdin deficiency associated with systemic meningococcal disease due to a novel p.Cys337Arg pathogenic variant
Laura González-Sánchez, Ana Mei Agudo, Anne Van Den Rym, [...], María Isabel Begiristain, Alazne Saizar, Rebeca Pérez de Diego, Pilar Nozal, Alberto López-Lera, Margarita López-Trascasa, Fernando Corvillo << Fewer
Published: 04 October 2023
2024, 11(6): 101134
Rapid Communication | Open Access
Whole exome sequencing identifies new susceptibility candidates underlying community-acquired pneumonia
Jacobo Pardo-Seco, Sandra Viz-Lasheras, Xabier Bello, [...], Alberto Gómez-Carballa, Alba Camino-Mera, Sara Pischedda, María José Currás-Tuala, Irene Rivero-Calle, Ana Dacosta-Urbieta, Fernando Caamaño-Viña, Carmen Rodríguez-Tenreiro Sánchez, Isabel Cifuentes, Cristina Méndez, Chiea Chuen Khor, Federico Martinón-Torres, Antonio Salas, on behalf of the CAPPRIC study group << Fewer
Published: 19 November 2023
2024, 11(6): 101170
Rapid Communication | Open Access
Performance analysis of markers for prostate cell typing in single-cell data
Yanting Shen, Xiawei Fei, Junyan Xu, [...], Rui Yang, Qinyu Ge, Zhong Wang << Fewer
Published: 26 October 2023
2024, 11(6): 101157
Rapid Communication | Open Access
CCDC178-mediated cytoskeleton assembly is required for spermiogenesis in mice
Fucheng Dong, Xiuge Wang, Tao Huang, [...], Yingying Yin, Sai Xiao, Yanjie Ma, Huafang Wei, Bingbing Wu, Ruidan Zhang, Liying Wang, Xuejiang Guo, Fei Gao, Chao Liu, Hongbin Liu, Jianguo Zhao, Wei Li << Fewer
Published: 29 September 2023
2024, 11(6): 101132
Rapid Communication | Open Access
Loss of homeostatic functions in microglia from a murine model of Friedreich’s ataxia
Ilaria Della Valle, Martina Milani, Simona Rossi, [...], Riccardo Turchi, Flavia Tortolici, Valentina Nesci, Alberto Ferri, Cristiana Valle, Daniele Lettieri-Barbato, Katia Aquilano, Mauro Cozzolino, Savina Apolloni, Nadia D’Ambrosi << Fewer
Published: 23 November 2023
2024, 11(6): 101178
Rapid Communication | Open Access
Precise and efficient insertion of A673T mutation in APP gene using MSYM
Qing Xia, Zijie Liu, Xinyu Yang, [...], Jiaying Xiao, Xue Zhao, Yu Zhao, Feifei Zheng, Fangliang Ge, Ke Ye, Lulu Liu, Dayong Wang, Xu Gao << Fewer
Published: 27 October 2023
2024, 11(6): 101154
Rapid Communication | Open Access
Factor analysis and subtyping significance of CTNNB1 gene mutation detection in adamantinomatous craniopharyngioma
Huarong Zhang, Chaohu Wang, Jun Fan, [...], Rongrong Guo, Qianchao Zhu, Jun Pan, Junxiang Peng, Zhiyong Wu, Songtao Qi, Yi Liu << Fewer
Published: 30 November 2023
2024, 11(6): 101188
Rapid Communication | Open Access
The mucolipidosis Ⅲ-causing mutation in GNPTAB, c.1760G>C, disrupts the development of somites in rats
Tianying Nong, Jiangui Li, Xia Li, [...], Yiqiang Li, Zhaohui Li, Weizhe Shi, Qiuchan Zhou, Hongwen Xu, Mingwei Zhu, Ya-Ping Tang << Fewer
Published: 17 November 2023
2024, 11(6): 101172
Rapid Communication | Open Access
Integrated analyses reveal the prognostic and immunotherapeutic value of endoplasmic reticulum stress-related genes in cancer
Qiuhua Lai, Lan Teng, Chengdong Liu, [...], Yihong Lai, Jianxin Chen, Fangyao Wu, Mengduo Lei, Side Liu, Chaojun Zhu, Xiaohan Zhou << Fewer
Published: 02 December 2023
2024, 11(6): 101187
Rapid Communication | Open Access
HJURP indicates poor prognosis of female breast cancer by promoting cell proliferation and migration
Wenquan Chen, Hao Li, Dandan Wang, [...], Sujin Yang, Junchen Hou, Honglei Zhou, Jinhai Tang, Jian Zhang << Fewer
Published: 23 November 2023
2024, 11(6): 101176
Rapid Communication | Open Access
Effect of FTO on cardiac hypertrophy through the regulation of OBSCN expression
Lili Chen, Yiheng Zhao, Wenjing Wang, [...], Shuchen Zhang, Xiang Zhou << Fewer
Published: 11 November 2023
2024, 11(6): 101165
Rapid Communication | Open Access
Constitutive androstane receptor: A tumor suppressor and a biomarker for favorable prognosis of liver diseases
Sarah Da Won Bae, Romario Nguyen, Lawrence Yuen, [...], Vincent Lam, Jacob George, Liang Qiao << Fewer
Published: 19 December 2023
2024, 11(6): 101198
Rapid Communication | Open Access
The silencing transcription factor REST targets UCHL1 to regulate inflammatory response and fibrosis during cardiac hypertrophy
Wenze Cao, Huan Liu, Ye Xu, [...], Sangyu Hu, Yujie Yang, Li Li, Luying Peng << Fewer
Published: 25 November 2023
2024, 11(6): 101183
Rapid Communication | Open Access
Simultaneous detection of methylation and genetic variations of BCR-ABL1 gene by nanopore Cas9-targeted sequencing
Shuilian Xie, Ying Yang, Junjie Zhang, [...], Menglin Zhu, Wang Li, Mengting Li, Yijian Chen, Hailiang Li, Weidan Lun, Weelic Chong, Shaogui Wan << Fewer
Published: 06 December 2023
2024, 11(6): 101190
Rapid Communication | Open Access
Biallelic inactivation of SDHA results in comorbidity of pediatric recurrent neuroblastoma and gastric stromal tumor
Shen Yang, Shixuan Zhang, Wen Zhao, [...], Libing Fu, Li Zhang, Chan Hon Chui, Ruolan Guo, Yan Su, Dayan Sun, Huanmin Wang << Fewer
Published: 15 December 2023
2024, 11(6): 101196
Rapid Communication | Open Access
Identification of immune cell infiltration pattern in diabetic nephropathy
Yongguang Liu, Xiaoyou Liu, Ding Liu, [...], Song Zhou, Jie Zhang, Jianmin Hu, Guorong Liao, Jun Liao, Zefeng Guo, Yuzhu Li, Siqiang Yang, Shichao Li, Hua Chen, Ying Guo, Min Li, Lipei Fan, Liuyang Li, Ming Zhao << Fewer
Published: 17 December 2023
2024, 11(6): 101197
Rapid Communication | Open Access
A novel homozygous intronic variant affecting splicing in the RYR1 gene contributes to fetal hydrops
Wei Hou, Guifang Huang, Hongyu Wei, [...], Wenwei Li, Houfeng Huang, Yuling Qiu, Hengying Zhu, Huifeng Han, Ping Chen, Xue Zhang << Fewer
Published: 14 July 2024
2024, 11(6): 101375
Rapid Communication | Open Access
Blood transcriptomic markers associated with immune abnormalities and sleep quality
Sang-Min Park, Hyo-Jeong Ban, Minsung Lee, [...], Soo Yeon Kim, Siwoo Lee, Hee-Jeong Jin << Fewer
Published: 14 September 2023
2024, 11(6): 101105
REVIEW ARTICLES
Review Article | Open Access
Focus on cardiac troponin complex: From gene expression to cardiomyopathy
Rosetta Ragusa, Chiara Caselli
Published: 11 March 2024
2024, 11(6): 101263
Review Article | Open Access
Exosome-mediated renal protection: Halting the progression of fibrosis
Chuanqi Liu, Qingfeng Li, Jian-Xing Ma, [...], Baisong Lu, Tracy Criswell, Yuanyuan Zhang << Fewer
Published: 19 September 2023
2024, 11(6): 101117
Review Article | Open Access
A comprehensive review of animal models for cancer cachexia: Implications for translational research
Li Li, Junaid Wazir, Zhiqiang Huang, [...], Yong Wang, Hongwei Wang << Fewer
Published: 13 September 2023
2024, 11(6): 101080
Review Article | Open Access
Understanding neurodevelopmental proteasomopathies as new rare disease entities: A review of current concepts, molecular biomarkers, and perspectives
Silvestre Cuinat, Stéphane Bézieau, Wallid Deb, [...], Sandra Mercier, Virginie Vignard, Bertrand Isidor, Sébastien Küry, Frédéric Ebstein << Fewer
Published: 26 September 2023
2024, 11(6): 101130
Review Article | Open Access
Single-cell spatial transcriptomics in cardiovascular development, disease, and medicine
Songjie Han, Qianqian Xu, Yawen Du, [...], Chuwei Tang, Herong Cui, Xiaofeng Xia, Rui Zheng, Yang Sun, Hongcai Shang << Fewer
Published: 14 November 2023
2024, 11(6): 101163
Review Article | Open Access
New insights into the cardio-renal benefits of SGLT2 inhibitors and the coordinated role of miR-30 family
Abdellatif El Khayari, Soukaina Miya Hakam, Gabriel Malka, [...], Luc Rochette, Rachid El Fatimy << Fewer
Published: 23 November 2023
2024, 11(6): 101174
Review Article | Open Access
Molecular mechanisms of cisplatin resistance in ovarian cancer
Chenying Jiang, Chenjun Shen, Maowei Ni, [...], Lili Huang, Hongtao Hu, Qinhui Dai, Huajun Zhao, Zhihui Zhu << Fewer
Published: 02 August 2023
2024, 11(6): 101063
Review Article | Open Access
Novel perspectives on leptin in osteoarthritis: Focus on aging
Zimo Liu, Wenqing Xie, Hengzhen Li, [...], Xu Liu, Yao Lu, Bangbao Lu, Zhenhan Deng, Yusheng Li << Fewer
Published: 04 November 2023
2024, 11(6): 101159
Review Article | Open Access
The implication of dendritic cells in lung diseases: Immunological role of toll-like receptor 4
Shurui Xuan, Yuan Ma, Honglei Zhou, [...], Shengwei Gu, Xin Yao, Xiaoning Zeng << Fewer
Published: 27 June 2023
2024, 11(6): 101007
Review Article | Open Access
Protein ubiquitination in ovarian cancer immunotherapy: The progress and therapeutic strategy
Huiling Guo, Jianwei Wei, Yuyan Zhang, [...], Li Wang, Junhu Wan, Weiwei Wang, Ling Gao, Jiajing Li, Ting Sun, Liwei Ma << Fewer
Published: 29 October 2023
2024, 11(6): 101158
Review Article | Open Access
NRF2 in age-related musculoskeletal diseases: Role and treatment prospects
Xiangyu Zhang, Hengzhen Li, Lin Chen, [...], Yuxiang Wu, Yusheng Li << Fewer
Published: 27 November 2023
2024, 11(6): 101180
Review Article | Open Access
Comprehensive multi-omics profiling identifies novel molecular subtypes of pancreatic ductal adenocarcinoma
Xing Wang, Jinshou Yang, Bo Ren, [...], Gang Yang, Xiaohong Liu, Ruiling Xiao, Jie Ren, Feihan Zhou, Lei You, Yupei Zhao << Fewer
Published: 14 October 2023
2024, 11(6): 101143
Review Article | Open Access
MDM2 inhibitors in cancer immunotherapy: Current status and perspective
Qinru Zeng, Shaocheng Zeng, Xiaofeng Dai, [...], Yun Ding, Chunye Huang, Ruiwen Ruan, Jianping Xiong, Xiaomei Tang, Jun Deng << Fewer
Published: 28 March 2024
2024, 11(6): 101279
Review Article | Open Access
Histone deacetylases: Regulation of vascular homeostasis via endothelial cells and vascular smooth muscle cells and the role in vascular pathogenesis
Hanyi Yang, Kai Guo, Peng Ding, [...], Jiayi Ning, Yimeng Zhang, Yuanyong Wang, Zhaoyang Wang, Guanglin Liu, Changjian Shao, Minghong Pan, Zhiqiang Ma, Xiaolong Yan, Jing Han << Fewer
Published: 22 January 2024
2024, 11(6): 101216
FULL LENGTH ARTICLES
Full Length Article | Open Access
GAPDH suppresses adenovirus-induced oxidative stress and enables a superfast production of recombinant adenovirus
Guozhi Zhao, Piao Zhao, Yonghui Wang, [...], Hui Zhang, Yi Zhu, Jiamin Zhong, Wulin You, Guowei Shen, Changqi Luo, Ou Mei, Xingye Wu, Jingjing Li, Yi Shu, Hongwei Wang, William Wagstaff, Hue H. Luu, Yang Bi, Lewis L. Shi, Russell R. Reid, Tong-Chuan He, Li Jiang, Wei Tang, Jiaming Fan, Ziwei Tang << Fewer
Published: 31 May 2024
2024, 11(6): 101344
Full Length Article | Open Access
Mitophagy deficiency activates stimulator of interferon genes activation and aggravates pathogenetic cardiac remodeling
Guoxiang Zhou, Xiaowen Wang, Mingyu Guo, [...], Can Qu, Lei Gao, Jiang Yu, Yuanjing Li, Suxin Luo, Qiong Shi, Yongzheng Guo << Fewer
Published: 02 September 2023
2024, 11(6): 101074
Full Length Article | Open Access
The proteasome activator subunit PSME1 promotes HBV replication by inhibiting the degradation of HBV core protein
Yu Liu, Jiaxin Yang, Yanyan Wang, [...], Qiqi Zeng, Yao Fan, Ailong Huang, Hui Fan << Fewer
Published: 14 October 2023
2024, 11(6): 101142
Full Length Article | Open Access
Elevated meteorin-like protein from high-intensity interval training improves heart function via AMPK/HDAC4 pathway
Yongshun Wang, Jie Yuan, Huadong Liu, [...], Jie Chen, Jieru Zou, Xiaoyi Zeng, Lei Du, Xin Sun, Zhengyuan Xia, Qingshan Geng, Yin Cai, Jingjin Liu << Fewer
Published: 14 September 2023
2024, 11(6): 101100
Full Length Article | Open Access
Single-cell RNA sequencing reveals a distinct profile of bone immune microenvironment and decreased osteoclast differentiation in type 2 diabetic mice
Zimei Wu, Qiaodan Hou, Heng Chi, [...], Jihong Liu, Yixin Mei, Tingting Chen, Kunkun Yang, Jingna Zheng, Jing Xu, Fuxin Wei, Lin Wang << Fewer
Published: 17 October 2023
2024, 11(6): 101145
Full Length Article | Open Access
The stability of FKBP9 maintained by BiP is crucial for glioma progression
Shirong Li, Wangxiao Xia, Bin Sun, [...], Weiyan Peng, Dong Yang, Jing Gao, Shuai He, Hua Yang, Yongjie Zhu, Hu Zhou, Tingxiu Xiang, Qingpeng Kong, Xudong Zhao << Fewer
Published: 22 September 2023
2024, 11(6): 101123
Full Length Article | Open Access
VPS13D affects epileptic seizures by regulating mitochondrial fission and autophagy in epileptic rats
Jian Wang, Fan Zhang, Zhong Luo, [...], Haiqing Zhang, Changyin Yu, Zucai Xu << Fewer
Published: 19 March 2024
2024, 11(6): 101266
Full Length Article | Open Access
STIM1 promotes acquired resistance to sorafenib by attenuating ferroptosis in hepatocellular carcinoma
Ran Ren, Yu Chen, Yu Zhou, [...], Luyao Shen, Yang Chen, Juan Lei, Jingchun Wang, Xudong Liu, Nan Zhang, Dongqin Zhou, Huakan Zhao, Yongsheng Li << Fewer
Published: 28 March 2024
2024, 11(6): 101281
Full Length Article | Open Access
Identification of ferroptosis-associated tumor antigens as the potential targets to prevent head and neck squamous cell carcinoma
Qiming Zhai, Zhiwei Wang, Han Tang, [...], Shanshan Hu, Meihua Chen, Ping Ji << Fewer
Published: 19 January 2024
2024, 11(6): 101212
Full Length Article | Open Access
Iron promotes both ferroptosis and necroptosis in the early stage of reperfusion in ischemic stroke
Bin Du, Zijie Deng, Kang Chen, [...], Zhangzhong Yang, Junfen Wei, Liuyao Zhou, Jie Meng, Ying Cheng, Xin Tian, Qing-Zhang Tuo, Peng Lei << Fewer
Published: 08 March 2024
2024, 11(6): 101262
Full Length Article | Open Access
Cancer-associated fibroblasts derived fibronectin extra domain A promotes sorafenib resistance in hepatocellular carcinoma cells by activating SHMT1
Yan Dong, Yanrong Chen, Yijie Wang, [...], Xiang Zhao, Ruiyang Zi, Jie Hao, Qiong Ding, Haoran Jiang, Xuesong Wang, Fanghao Lu, Houjie Liang, Zhihao Wei, Jianjun Li << Fewer
Published: 20 May 2024
2024, 11(6): 101330
Full Length Article | Open Access
Gene interactions analysis of brain spatial transcriptome for Alzheimer’s disease
Shengran Wang, Jonathan Greenbaum, Chuan Qiu, [...], Russell H. Swerdlow, Mohammad Haeri, Yun Gong, Hui Shen, Hongmei Xiao, Hongwen Deng << Fewer
Published: 22 May 2024
2024, 11(6): 101337
CORRIGENDA
Corrigendum | Open Access
Corrigendum to “N6-methyladenosine modified LINC00901 promotes pancreatic cancer progression through IGF2BP2/MYC axis” [Genes & Diseases 10 (2023) 554—567]
Wan-Xin Peng, Fei Liu, Jia-Hong Jiang, [...], Hang Yuan, Ziqiang Zhang, Liu Yang, Yin-Yuan Mo << Fewer
Published: 15 June 2024
2024, 11(6): 101352
Corrigendum | Open Access
Corrigendum to ‘CRISPR/Cas9 system and its applications in nervous system diseases’ [Genes & Diseases 11 (2024) 675–686]
Haibin Jiang, Mengyan Tang, Zidi Xu, [...], Yanan Wang, Mopu Li, Shuyin Zheng, Jianghu Zhu, Zhenlang Lin, Min Zhang << Fewer
Published: 19 August 2024
2024, 11(6): 101392