RT Journal Article A1 Lu Zhou,Liping Chen,Zhenyao Ding,Dandan Wang,Hao Xie,Weihai Ni,Weixiang Ye,Xiqi Zhang,Lei Jiang,Xinjian Feng; AD 材料与化学化工学部, 中国 ; 材料与化学化工学部, 中国 ; 材料与化学化工学部, 中国 ; 材料与化学化工学部, 中国 ; 江苏省薄膜材料重点实验室, 中国 ; 江苏省薄膜材料重点实验室, 中国 ; 江苏省薄膜材料重点实验室, 中国 ; 苏州能源与材料创新研究所, 中国 ; 未来技术学院, 中国 ; 生物仿生材料与界面科学重点实验室, 中国 ; 材料与化学化工学部, 中国 T1 Enhancement of interfacial catalysis in a triphase reactor using oxygen nanocarriers YR 2021 IS 1 vo 14 OP 172-OP 176 K1 biocatalysis;oxidase kinetics;triphase interface;oil core-silica shell sphere AB Multiphase catalysis is used in many industrial processes; however, the reaction rate can be restricted by the low accessibility of gaseous reactants to the catalysts in water, especially for oxygen-dependent biocatalytic reactions. Despite the fact that solubility and diffusion rates of oxygen in many liquids (such as perfluorocarbon) are much higher than in water, multiphase reactions with a second liquid phase are still difficult to conduct, because the interaction efficiency between immiscible phases is extremely low. Herein, we report an efficient triphase biocatalytic system using oil core-silica shell oxygen nanocarriers. Such design offers the biocatalytic system an extremely large water-solid-oil triphase interfacial area and a short path required for oxygen diffusion. Moreover, the silica shell stabilizes the oil nanodroplets in water and prevents their aggregation. Using oxygen-dependent oxidase enzymatic reaction as an example, we demonstrate this efficient biocatalytic system for the oxidation of glucose, choline, lactate, and sucrose by substituting their corresponding oxidase counterparts. A rate enhancement by a factor of 10-30 is observed when the oxygen nanocarriers are introduced into reaction system. This strategy offers the opportunity to enhance the efficiency of other gaseous reactants involved in multiphase catalytic reactions. SN 1998-0124 LA EN