{Reference Type}: Journal Article {Title}: Fabrication of carbon coated gadolinia particles for dual-mode magnetic resonance and fluorescence imaging {Author}: ATABAEV, Timur Sh.; LEE, Jong Ho; HAN, Dong-Wook; KIM, Hyung-Kook; Yoon-Hwae, HWANG {Journal}: Journal of Advanced Ceramics {ISBN/ISSN}: 2226-4108 {Year}: 2015 {Volume}: 4 {Issue}: 2 {Pages}: 118-122 {DOI}: 10.1007/s40145-015-0139-z {Keywords}: carbon {Keywords}: fluorescence {Keywords}: core–shell structure {Keywords}: gadolinia particles {Keywords}: magnetic resonance imaging (MRI) contrast agent {Abstract}: In the present study, we report a fabrication of dual-mode carbon coated gadolinia C@Gd2O3 particles by a facile hydrothermal synthesis method without using any organic solvents. The prepared C@Gd2O3 particles have a core–shell structure and a narrow size distribution in the range of 261±27 nm. The fluorescent properties of the prepared C@Gd2O3 particles were accessed by a room-temperature photoluminescence study, while the longitudinal relaxivity (r1) was examined by using a clinical 1.5 T MRI scanner. A murine fibroblast L-929 cell line was used to examine the cytotoxicity and capability of the prepared C@Gd2O3 particles for the fluorescent labeling. The obtained results show that the prepared C@Gd2O3 particles could be used as a dual-mode contrast agent for magnetic resonance and fluorescence imaging. {URL}: https://www.sciopen.com/article/10.1007/s40145-015-0139-z {Language}: en