TY - JOUR AU - Jia, Mochen AU - Chen, Xu AU - Sun, Ranran AU - Wu, Di AU - Li, Xinjian AU - Shi, Zhifeng AU - Chen, Guanying AU - Shan, Chongxin PY - 2023 TI - Lanthanide-based ratiometric luminescence nanothermometry JO - Nano Research SN - 1998-0124 SP - 2949 EP - 2967 VL - 16 IS - 2 AB - Luminescent nanothermometry can precisely and remotely measure the internal temperature of objects at nanoscale precision, which, therefore, has been placed at the forefront of scientific attention. In particular, due to the high photochemical stability, low toxicity, rich working mechanisms, and superior thermometric performance, lanthanide-based ratiometric luminesencent thermometers are finding prevalent uses in integrated electronics and optoelectronics, property analysis of in-situ tracking, biomedical diagnosis and therapy, and wearable e-health monitoring. Despite recent progresses, it remains debate in terms of the underlying temperature-sensing mechanisms, the quantitative characterization of performance, and the reliability of temperature readouts. In this review, we show the origin of thermal response luminescence, rationalize the ratiometric scheme or thermometric mechanisms, delve into the problems in the characterization of thermometric performance, discuss the universal rules for the quantitative comparison, and showcase the cutting-edge design and emerging applications of lanthanide-based ratiometric thermometers. Finally, we cast a look at the challenges and emerging opportunities for further advances in this field. UR - https://doi.org/10.1007/s12274-022-4882-7 DO - 10.1007/s12274-022-4882-7