@article{LIANG2026, 
author = {Jia’en LIANG and Zhuole WU and Xiangxiang JING},
title = {Research progress on the application of sonodynamic therapy in the treatment of melanoma},
year = {2026},
journal = {Journal of Nanjing Medical University (Natural Sciences)},
volume = {46},
number = {9},
pages = {1421-1428},
keywords = {melanoma, sonodynamic therapy, sonosensitizer, nanomedicine},
url = {https://www.sciopen.com/article/10.7655/NYDXBNSN260345},
doi = {10.7655/NYDXBNSN260345},
abstract = {Melanoma is a kind of malignant skin cancer with a high mortality rate. Currently, the treatment of advanced melanoma remains a challenging issue as conventional treatments such as surgery, chemotherapy and radiotherapy offer limited benefits. Sonodynamic therapy (SDT) offers advantages such as high efficiency, simplicity, and less invasiveness. However, a major limitation is the difficulty in identifying suitable sonosensitizers that can ensure effective treatment outcome. With the gradual development of nanomedicine technology, the synthesized nano-sonosensitizers can resolve the limitations of SDT and enhance the therapeutic efficacy, making SDT a promising novel approach for the treatment of advanced melanoma. This article aims to review recent advances in sonosensitizers for sonodynamic therapy of melanoma and evaluate their therapeutic effects.}
}