@article{SHI2025, 
author = {Lifeng SHI and Yan WU and Guangyong WANG and Shaoyu ZHANG and Fang WANG and Tao GUO and Guangman TANG and Lan LI and Yibing ZHOU},
title = {Change in serum uric acid level and its influencing factors among military personnel during long-term maritime mission},
year = {2025},
journal = {Journal of Army Medical University},
volume = {47},
number = {12},
pages = {1284-1290},
keywords = {long-term maritime, uric acid, aerobic exercise, psychology and health},
url = {https://www.sciopen.com/article/10.16016/j.2097-0927.202408043},
doi = {10.16016/j.2097-0927.202408043},
abstract = {ObjectiveTo investigate the characteristics of changes in blood uric acid (UA) and detection rate of hyperuricemia (HUA) among officers and soldiers during long-term maritime missions, as well as their related influencing factors.MethodsA total of 100 servicemen were randomly selected from 240 officers and soldiers who will participate in a long-distance voyage mission. Their general information, including age, education level, administrative position, years of service on board, and department, was surveyed. Their annual data of physical examination were retrospectively analyzed and compared with the results of another 335 shore-based servicemen during the same period. On mission day 10 (D10) and day 50 (D50), the venous blood samples were collected from the participants to synchronously measure blood UA level and body composition indicators (body fat mass, BMI, fat percentage, fat mass, muscle mass, and muscle percentage). Additionally, on D50, Self-Rating Scale of Sleep (SRSS) and Symptom Checklist-90 (SCL-90) were employed to survey their conditions. Seventy service members were randomly selected from the 100 participants to engage in aerobic exercise. The changes in UA level and detection rate of HUA among the mission personnel were analyzed, along with their influencing factors.ResultsThe UA level and HUA detection rate in long-term navigation personnel during concurrent annual physical examinations were significantly lower than those in shore-based personnel (P<0.01). Compared to pre-voyage physical examination results, the UA level and HUA detection rate in long-term navigation personnel were significantly increased from mission day D10 (P<0.001). Compared to the values at D10, the UA level and HUA detection rate at D50 showed significant decreases (P<0.05), and then essentially returned to pre-mission examination levels (P>0.05). Aged <32 years was an independent risk factor for new-onset HUA at mission D10 (P<0.05). <32 years old and aerobic exercise during the voyage were independent influencing factors for HUA outcome (P<0.05).ConclusionSerum UA level and HUA detection rate among officers and soldiers participating in long-term maritime missions are relatively low before departure, but in significant increases during the early stages of the mission, particularly among those aged <32 years. Scientific aerobic exercise during the mission period helps reduce UA level and HUA detection rate, playing a crucial role in guaranteeing physical and mental health.}
}