@article{Wang2025, 
author = {Zitong Wang and Feng Zhao and Hongxin Lang and Haiyue Ren and Qiqi Zhang and Xing Huang and Cai He and Chengcheng Xu and Chiyu Tan and Jiajie Ma and Shu Duan and Zhe Wang},
title = {Organoids in skin wound healing},
year = {2025},
journal = {Burns & Trauma},
volume = {13},
number = {1},
pages = {tkae077},
keywords = {Skin organoids, Tissue engineering, Pluripotent stem cells, Skin wound healing},
url = {https://www.sciopen.com/article/10.1093/burnst/tkae077},
doi = {10.1093/burnst/tkae077},
abstract = {Stem cells (SCs) can self-replicate and differentiate into multiple lineages. Organoids, 3D cultures derived from SCs, can replicate the spatial structure and physiological characteristics of organs in vitro. Skin organoids can effectively simulate the physiological structure and function of skin tissue, reliably restoring the natural skin ecology in various in vitro environments. Skin organoids have been employed extensively in skin development and pathology research, offering valuable insights for drug screening. Moreover, they play crucial roles in skin regeneration and tissue repair. This in-depth review explores the construction and applications of skin organoids in wound healing, with a focus on their construction process, including skin appendage integration, and significant advancements in wound-healing research.}
}